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GSK 264220A - ≥98%(HPLC), high purity , CAS No.685506-42-7, Inhibitor of lipase G; endothelial type
Endothelial lipase and lipoprotein lipase inhibitor
Basic Description
| Synonyms | N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea | 3-[2-methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea | DTXSID30384608 | HMS2799K10 | Q27077890 | SR-01000774442 | CCG-242835 | NCGC00344077-02 | SMR000456118 | HY-103372 | GTPL6697 |
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| Specifications & Purity | Moligand™, ≥98%(HPLC) |
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| Biochemical and Physiological Mechanisms | Endothelial lipase and lipoprotein lipase inhibitor (IC50values are 0.13 and 0.10μM respectively). |
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| Storage Temp | Store at 2-8°C |
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| Shipped In | Wet ice |
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| Grade | Moligand™ |
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| Action Type | INHIBITOR |
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| Mechanism of action | Inhibitor of lipase G; endothelial type |
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Associated Targets(Human)
Associated Targets(non-human)
Names and Identifiers
| IUPAC Name | 1-(2-methyl-5-piperidin-1-ylsulfonylfuran-3-yl)-3-phenylurea |
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| INCHI | InChI=1S/C17H21N3O4S/c1-13-15(19-17(21)18-14-8-4-2-5-9-14)12-16(24-13)25(22,23)20-10-6-3-7-11-20/h2,4-5,8-9,12H,3,6-7,10-11H2,1H3,(H2,18,19,21) |
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| InChi Key | LVOVQRPAMXCXTM-UHFFFAOYSA-N |
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| Canonical SMILES | CC1=C(C=C(O1)S(=O)(=O)N2CCCCC2)NC(=O)NC3=CC=CC=C3 |
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| Isomeric SMILES | CC1=C(C=C(O1)S(=O)(=O)N2CCCCC2)NC(=O)NC3=CC=CC=C3 |
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| PubChem CID | 2810413 |
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| Molecular Weight | 363.43 |
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Chemical and Physical Properties
| Solubility | Solvent:DMSO, Max Conc. mg/mL: 36.34, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 3.63, Max Conc. mM: 10 |
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