Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G274953-5mg | 5mg | In stock | $47.90 | |
G274953-10mg | 10mg | In stock | $77.90 | |
G274953-25mg | 25mg | In stock | $175.90 | |
G274953-50mg | 50mg | In stock | $338.90 | |
G274953-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $599.90 |
Selective ERRβγ agonist
Synonyms | J-000435 | GSK 4716, >=98% (HPLC) | EN300-6474545 | 2gpp | CHEBI:80000 | A16956 | MFCD00567155 | CS-D0397 | 4-hydroxy-N''-[(1E)-[4-(propan-2-yl)phenyl]methylidene]benzohydrazide | 4-hydroxy-N'-[(E)-[4-(propan-2-yl)phenyl]methylidene]benzohydrazide | HY-33 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | GSK 4716 is an Estrogen-related receptors ERRβ and ERRγ agonist with minimal activity for ERRα, ERα and Erβ |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of Estrogen-related receptor-γ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at +4°C. The product can be stored for up to 12 months. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 4-hydroxy-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]benzamide |
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INCHI | InChI=1S/C17H18N2O2/c1-12(2)14-5-3-13(4-6-14)11-18-19-17(21)15-7-9-16(20)10-8-15/h3-12,20H,1-2H3,(H,19,21)/b18-11+ |
InChi Key | IKPPIUNQWSRCOZ-WOJGMQOQSA-N |
Canonical SMILES | CC(C)C1=CC=C(C=C1)C=NNC(=O)C2=CC=C(C=C2)O |
Isomeric SMILES | CC(C)C1=CC=C(C=C1)/C=N/NC(=O)C2=CC=C(C=C2)O |
PubChem CID | 5331325 |
Molecular Weight | 282.34 |
PubChem CID | 5331325 |
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CAS Registry No. | 101574-65-6 |
ChEMBL Ligand | CHEMBL193836 |
NURSA Ligand | 10.1621/78IFCC39I5 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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A2206008 | Certificate of Analysis | Jul 12, 2023 | G274953 |
A2206051 | Certificate of Analysis | Jul 12, 2023 | G274953 |
A2206059 | Certificate of Analysis | Jul 12, 2023 | G274953 |
A2206062 | Certificate of Analysis | Jul 12, 2023 | G274953 |
A2206064 | Certificate of Analysis | Jul 12, 2023 | G274953 |
Solubility | Soluble in DMSO to 100 mM and in ethanol to 100 mM |
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Pictogram(s) | GHS09, GHS07 |
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Signal | Warning |
Hazard Statements | H317:May cause an allergic skin reaction H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. |