Basic Description

Synonyms	101574-65-6 \| GSK 4716 \| GSK4716 \| 4-hydroxy-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]benzamide \| CHEBI:80000 \| Benzoic acid, 4-hydroxy-, 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide \| 4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide \| 4-Hydroxy-2-[(1E)-[4-(1
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	GSK 4716 is an Estrogen-related receptors ERRβ and ERRγ agonist with minimal activity for ERRα, ERα and Erβ
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Product Description	Store at +4°C. The product can be stored for up to 12 months.

Associated Targets(Human)

ESRRG Tchem Estrogen-related receptor gamma (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ESRRA Tchem Estrogen-related receptor alpha (573 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ESRRG Tchem Estrogen-related receptor gamma (587 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

U2OS (164939 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Alpha trans-inducing protein (VP16) (945 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

IUPAC Name	4-hydroxy-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]benzamide
INCHI	InChI=1S/C17H18N2O2/c1-12(2)14-5-3-13(4-6-14)11-18-19-17(21)15-7-9-16(20)10-8-15/h3-12,20H,1-2H3,(H,19,21)/b18-11+
InChi Key	IKPPIUNQWSRCOZ-WOJGMQOQSA-N
Canonical SMILES	CC(C)C1=CC=C(C=C1)C=NNC(=O)C2=CC=C(C=C2)O
Isomeric SMILES	CC(C)C1=CC=C(C=C1)/C=N/NC(=O)C2=CC=C(C=C2)O
PubChem CID	5331325
Molecular Weight	282.34

Enter Lot Number to search for COA:

Pictogram(s)	GHS09, GHS07
Signal	Warning
Hazard Statements	H317:May cause an allergic skin reaction H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage.

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.