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GSK 9027 - ≥98%(HPLC), high purity , CAS No.1229096-88-1

≥98%(HPLC)

CAS#: 1229096-88-1
Formula: C₂₇H₁₉F₄N₃O₂S
Molecular Weight: 525.52
PubChem CID: 24882669

Item Number

G288349

Grouped product items
SKU	Size	Availability	Price	Qty
G288349-10mg	10mg	In stock	$196.90
G288349-50mg	50mg	In stock	$807.90

Glucocorticoid receptor agonist

Specifications & Purity

≥98%(HPLC)

Biochemical and Physiological Mechanisms

Glucocorticoid receptor agonist (pIC50= 8). Inhibits production of the proinflammatory mediator IL-6in vivo.

Storage Temp

Room temperature

Shipped In

Normal

Associated Targets(Human)

NR3C1 Tclin Glucocorticoid receptor (3 Activities)

Discover Target: NR3C1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PGR Tclin Progesterone receptor (8562 Activities)

Discover Target: PGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Discover Target:

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	N-[4-[1-(4-fluorophenyl)indazol-5-yl]-3-(trifluoromethyl)phenyl]-1-phenylmethanesulfonamide
INCHI	InChI=1S/C27H19F4N3O2S/c28-21-7-10-23(11-8-21)34-26-13-6-19(14-20(26)16-32-34)24-12-9-22(15-25(24)27(29,30)31)33-37(35,36)17-18-4-2-1-3-5-18/h1-16,33H,17H2
InChi Key	DXBJGDVBQPEMOB-UHFFFAOYSA-N
Canonical SMILES	C1=CC=C(C=C1)CS(=O)(=O)NC2=CC(=C(C=C2)C3=CC4=C(C=C3)N(N=C4)C5=CC=C(C=C5)F)C(F)(F)F
Isomeric SMILES	C1=CC=C(C=C1)CS(=O)(=O)NC2=CC(=C(C=C2)C3=CC4=C(C=C3)N(N=C4)C5=CC=C(C=C5)F)C(F)(F)F
PubChem CID	24882669
Molecular Weight	525.52

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
C2425293	Certificate of Analysis	Mar 07, 2024	G288349
C2425294	Certificate of Analysis	Mar 07, 2024	G288349
C2425295	Certificate of Analysis	Mar 07, 2024	G288349
C2425296	Certificate of Analysis	Mar 07, 2024	G288349

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GSK 9027 - ≥98%(HPLC), high purity , CAS No.1229096-88-1

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

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