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1.14.13.9 Kynurenine 3-monooxygenase
GSK180 , CAS No.G610694, Inhibitor of kynurenine 3-monooxygenase

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GSK180 , CAS No.G610694, Inhibitor of kynurenine 3-monooxygenase

Moligand™

PubChem CID: 105539874

Item Number

G610694

Grouped product items
SKU	Size	Availability	Price	Qty
G610694-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$572.90
G610694-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

kynurenine 3-monooxygenase Inhibitor

Basic Description

Synonyms	inhibitor A1
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of kynurenine 3-monooxygenase

Associated Targets(Human)

KMO Tchem Kynurenine 3-monooxygenase (2 Activities)

Discover Target: KMO

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ALB Tchem Serum albumin (2651 Activities)

Discover Target: ALB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KMO Tchem Kynurenine 3-monooxygenase (379 Activities)

Discover Target: KMO

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Rattus norvegicus (775804 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-(5,6-dichloro-2-oxo-1,3-benzoxazol-3-yl)propanoic acid
INCHI	InChI=1S/C10H7Cl2NO4/c11-5-3-7-8(4-6(5)12)17-10(16)13(7)2-1-9(14)15/h3-4H,1-2H2,(H,14,15)
InChi Key	MIGAKMWKMLYGJX-UHFFFAOYSA-N
Canonical SMILES	OC(=O)CCn1c(=O)oc2c1cc(Cl)c(c2)Cl
Isomeric SMILES	C1=C2C(=CC(=C1Cl)Cl)OC(=O)N2CCC(=O)O
PubChem CID	105539874

Database links

PubChem CID	105539874
RCSB PDB Ligand	JHY

Certificates

Certificate of Analysis(COA)

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References

1. Mole DJ, Webster SP, Uings I, Zheng X, Binnie M, Wilson K, Hutchinson JP, Mirguet O, Walker A, Beaufils B et al.. (2016) Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis.. Nat Med, 22 (2): (202-9). [PMID:26752518] [10.1021/op500134e]

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