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GSK2606414 - ≥98%, high purity , CAS No.1337531-36-8

≥98%

CAS#: 1337531-36-8
Formula: C₂₄H₂₀F₃N₅O
Molecular Weight: 451.44
PubChem CID: 53469448

Item Number

G125654

Grouped product items
SKU	Size	Availability	Price
G125654-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$116.90
G125654-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$526.90
G125654-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$640.90

Discover GSK2606414 by Aladdin Scientific in ≥98% for only $116.90. Available - in Ligands at Aladdin Scientific. Potent and selective PERK inhibitor Tags: .

Basic Description

Synonyms	GSK2606414\|1337531-36-8\|GSK 2606414\|GSK-2606414\|1-(5-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)indolin-1-yl)-2-(3-(trifluoromethyl)phenyl)ethanone\|DPP2K6EFW8\|CHEMBL2171124\|1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-indolin-1-yl)-2-(3-
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Product Description	GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM, displaying at least 100-fold selectivity over the other EIF2AKs assayed.

Associated Targets

CYP2C8 Tchem Cytochrome P450 2C8 1 Activities

Discover Target: CYP2C8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

EIF2AK3 Tchem Eukaryotic translation initiation factor 2-alpha kinase 3 2 Activities

Discover Target: EIF2AK3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RIPK1 Tchem Receptor-interacting serine/threonine-protein kinase 1 1 Activities

Discover Target: RIPK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-[3-(trifluoromethyl)phenyl]ethanone
INCHI	InChI=1S/C24H20F3N5O/c1-31-12-18(21-22(28)29-13-30-23(21)31)15-5-6-19-16(11-15)7-8-32(19)20(33)10-14-3-2-4-17(9-14)24(25,26)27/h2-6,9,11-13H,7-8,10H2,1H3,(H2,28,29,30)
InChi Key	SIXVRXARNAVBTC-UHFFFAOYSA-N
Canonical SMILES	CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
Isomeric SMILES	CN1C=C(C2=C(N=CN=C21)N)C3=CC4=C(C=C3)N(CC4)C(=O)CC5=CC(=CC=C5)C(F)(F)F
PubChem CID	53469448
Molecular Weight	451.44

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2 results found

Lot Number	Certificate Type	Date	Item
L2322055	Certificate of Analysis	Jan 02, 2024	G125654
K1630020	Certificate of Analysis	Jun 17, 2022	G125654

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