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GSK319347A - ≥97%, high purity , CAS No.862812-98-4
Discover GSK319347A by Aladdin Scientific in ≥97% for only $137.90. Available - in Ligands at Aladdin Scientific. Inhibitor of IκB kinases (IKK) Tags: .
Basic Description Synonyms 862812-98-4|IKK-3 Inhibitor|GSK319347A|CAY10576|GSK-319347A|IKK-3 Inhibitor IX|5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile|5-(5,6-DIMETHOXYBENZIMIDAZOL-1-YL)-3-(2-METHANESULFONYL-BENZYLOXY)-THIOPHEN Specifications & Purity ≥97% Storage Temp Protected from light,Store at -20°C,Desiccated Shipped In Dry ice Product Description Product Describtion:
GSK319347A is a dual inhibitor of TBK1 and IKKε with IC50s of 93 nM and 469 nM, respectively. GSK319347A also inhibits IKK2 with an IC50 of 790 nM.
Names and Identifiers IUPAC Name 5-(5,6-dimethoxybenzimidazol-1-yl)-3-[(2-methylsulfonylphenyl)methoxy]thiophene-2-carbonitrile INCHI InChI=1S/C22H19N3O5S2/c1-28-17-8-15-16(9-18(17)29-2)25(13-24-15)22-10-19(20(11-23)31-22)30-12-14-6-4-5-7-21(14)32(3,26)27/h4-10,13H,12H2,1-3H3 InChi Key LDTAHRLHGHFHKP-UHFFFAOYSA-N Canonical SMILES COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C#N)OCC4=CC=CC=C4S(=O)(=O)C)OC Isomeric SMILES COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C#N)OCC4=CC=CC=C4S(=O)(=O)C)OC PubChem CID 11626927 Molecular Weight 469.53
Chemical and Physical Properties Solubility Soluble in DMSO Sensitivity Light sensitive
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I2307605