GSK319347A - ≥97%, high purity , CAS No.862812-98-4

Item Number

I274644

• Synonyms: benzimidazole-thiophene carbonitrile, 12e | CHEBI:91459 | IKK-3 Inhibitor | EINECS 211-880-2 | BRD-K51781482-001-02-1 | HMS3229F19 | LDTAHRLHGHFHKP-UHFFFAOYSA-N | AKOS002364333 | HMS3303L12 | SCHEMBL3413628 | BCP24906 | MS-28676 | HMS3305M09 | HY-14682 |
• Specifications & Purity: ≥97%
• Biochemical and Physiological Mechanisms: Key regulator of NF-κB signaling. Inhibitor of IκB kinases (IKK). One of three IKK isoforms-α, β, and ε-which have been linked to oncogenesis.
• Storage Temp: Protected from light,Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Product Describtion:

GSK319347A is a dual inhibitor of TBK1 and IKKε with IC50s of 93 nM and 469 nM, respectively. GSK319347A also inhibits IKK2 with an IC50 of 790 nM.