GSK690693 - ≥98%, high purity , Protein kinase C (PKC) inhibitor, CAS No.937174-76-0, Protein kinase C (PKC) inhibitor

Item Number

G127527

• Synonyms: (R)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-yl-MeO)-1H-imidazo[4,5-c]pyridin-4-yl)-2-Me-but-3-yn-2-ol | UNII-GWH480321B | AKOS015904356 | NCGC00263181-01 | (-)-4-(2-(4-AMINO-1,2,5-OXADIAZOL-3-YL)-1-ETHYL-7-((3S)-3-PIPERIDINYLMETHOXY)-1H
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: GSK-690693 is an ATP-competitive pan-Akt kinase inhibitor (IC50 values are 2, 13 and 9 nM for Akt1, 2 and 3 respectively). GSK-690693 also exhibits some inhibition for AMPK, PKA and PAK and PKC isoforms (IC50 < 100 nM). GSK-690693 displays antiprolifer
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Protein kinase C (PKC) inhibitor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Novel ATP-competitive pan-Akt kinase inhibitor.
GSK690693 has been used in western blotting and immunoprecipitations.