GSK872 - ≥98%, high purity , CAS No.1346546-69-7

Item Number

G276439

• Synonyms: GSK′872 | N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: GSK-872 is a RIPK3 inhibitor that binds to the RIP3 kinase domain with high affinity, with an IC50 of 1.8 nM, and inhibits kinase activity, with an IC50 of 1.3 nM. GSK-872 reduces RIPK3 mediated necroptosis and subsequent cytoplasmic translocation and exp
• Storage Temp: Protected from light,Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Note: Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

GSK'872 is a potent and selective RIP3 kinase inhibitor which binds RIP3 kinase domain with high affinity (IC50=1.8 nM) and inhibits kinase activity with IC50 of 1.3 nM. It has minimal cross-reactivity.