GT-0198 , CAS No.G610742, Inhibitor of GlyT2

Item Number
G610742
Grouped product items
SKUSizeAvailabilityPrice Qty
G610742-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$572.90
G610742-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
View related series
GlyT2 Inhibitor

Basic Description

SynonymsGT0198
Specifications & PurityMoligand™
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of GlyT2

Associated Targets(Human)

SLC6A5 Tchem Sodium- and chloride-dependent glycine transporter 2 (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A5 Tchem Glycine transporter 2 (697 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name N-(1-methylpiperidin-4-yl)-4-[[4-(trifluoromethyl)phenoxy]methyl]benzamide
INCHI InChI=1S/C21H23F3N2O2/c1-26-12-10-18(11-13-26)25-20(27)16-4-2-15(3-5-16)14-28-19-8-6-17(7-9-19)21(22,23)24/h2-9,18H,10-14H2,1H3,(H,25,27)
InChi Key IVOIYPHGIHJNMU-UHFFFAOYSA-N
Canonical SMILES CN1CCC(CC1)NC(=O)c1ccc(cc1)COc1ccc(cc1)C(F)(F)F
Isomeric SMILES CN1CCC(CC1)NC(=O)C2=CC=C(C=C2)COC3=CC=C(C=C3)C(F)(F)F
PubChem CID 71584823

Certificates

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Related Documents

References

1. Omori Y, Nakajima M, Nishimura K, Takahashi E, Arai T, Akahira M, Suzuki T, Kainoh M.  (2015)  Analgesic effect of GT-0198, a structurally novel glycine transporter 2 inhibitor, in a mouse model of neuropathic pain..  J Pharmacol Sci,  127  (3): (377-81).  [PMID:25837937]

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