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guanosine 5'-diphosphate , CAS No.146-91-8, Activator of K ir6.1
Basic Description
| Synonyms | 1fzq | guanosine-diphosphate | A808566 | Guanosine 5'-(trihydrogen diphosphate-P-32P) (9CI) | ((2R,3S,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate | [(2R,3S,4R,5R)-5-(2-amino-6-hydroxypurin-9- |
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| Specifications & Purity | Moligand™ |
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| Grade | Moligand™ |
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| Action Type | ACTIVATOR |
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| Mechanism of action | Activator of K ir6.1 |
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Associated Targets(Human)
Associated Targets(non-human)
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate |
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| INCHI | InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1 |
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| InChi Key | QGWNDRXFNXRZMB-UUOKFMHZSA-N |
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| Canonical SMILES | C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N |
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| Isomeric SMILES | C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N |
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| Alternate CAS | 157420-46-7,146-91-8 |
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| PubChem CID | 135398619 |
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| MeSH Entry Terms | 5'-Diphosphate, Guanosine;5'-Trihydrogen Diphosphate, Guanosine;Diphosphate, Guanosine;Diphosphate, Guanosine 5'-Trihydrogen;GDP;Guanosine 5' Diphosphate;Guanosine 5' Trihydrogen Diphosphate;Guanosine 5'-Diphosphate;Guanosine 5'-Trihydrogen Diphosphate;Gu |
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Citations of This Product
| 1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729] [10.1007/s44211-023-00430-5] |
| 2. Yuqin Wang, Pingping Fan, Shanyu Zhang, Liying Wang, Xinyue Li, Wendong Jia, Yao Liu, Kefan Wang, Xiaoyu Du, Panke Zhang, Shuo Huang. (2022) Discrimination of Ribonucleoside Mono-, Di-, and Triphosphates Using an Engineered Nanopore. ACS Nano, 16 (12): (21356–21365). [PMID:36475606] [10.1021/acsnano.2c09662] |
References
| 1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729] [10.1007/s44211-023-00430-5] |
| 2. Yuqin Wang, Pingping Fan, Shanyu Zhang, Liying Wang, Xinyue Li, Wendong Jia, Yao Liu, Kefan Wang, Xiaoyu Du, Panke Zhang, Shuo Huang. (2022) Discrimination of Ribonucleoside Mono-, Di-, and Triphosphates Using an Engineered Nanopore. ACS Nano, 16 (12): (21356–21365). [PMID:36475606] [10.1021/acsnano.2c09662] |
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