Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
G286659-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $19.90 | |
G286659-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $99.90 | |
G286659-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $219.90 | |
G286659-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $399.90 |
Selective PPARγ agonist
Specifications & Purity | ≥98%(HPLC) |
---|---|
Biochemical and Physiological Mechanisms | Highly selective orally active peroxisome proliferator-activated receptor (PPAR)γagonist (pEC50values are 8.05, < 4 and < 4 for human PPARγ, PPARαand PPARδreceptors respectively). Decreases glucose, fatty acid and triglyceride levels following oral admini |
Storage Temp | Store at -20°C,Desiccated |
Shipped In | Ice chest + Ice pads |
Product Description |
Highly selective orally active peroxisome proliferator-activated receptor (PPAR)γ agonist (pEC50 values are 8.05, < 4 and < 4 for human PPARγ, PPARα and PPARδ receptors respectively). Decreases glucose, fatty acid and triglyceride levels following oral administration in vivo.
|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
---|
IUPAC Name | (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid;hydrochloride |
---|---|
INCHI | InChI=1S/C30H29N3O4.ClH/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23;/h2-18,27,32H,19-21H2,1H3,(H,35,36);1H/t27-;/m0./s1 |
InChi Key | KXNKIKXTGRMLEY-YCBFMBTMSA-N |
Canonical SMILES | CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4.Cl |
Isomeric SMILES | CN(CCOC1=CC=C(C=C1)C[C@@H](C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4.Cl |
Alternate CAS | 196808-24-9 |
PubChem CID | 56972174 |
Molecular Weight | 532.03 |
Enter Lot Number to search for COA:
Solubility | Solvent:ethanol, Max Conc. mg/mL: 49.56, Max Conc. mM: 100 with gentle warming; Solvent:water, Max Conc. mg/mL: 26.6, Max Conc. mM: 50 |
---|