GW 766994 - 10mM in DMSO, high purity , CAS No.408303-43-5(DMSO)

Item Number

G654579

• Specifications & Purity: Moligand™, 10mM in DMSO
• Storage Temp: Store at -80°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™

Product Description

GW 766994 (GW 994) is an orally active and specific chemokine receptor-3 (CCR3) antagonist. GW 766994 has the potential for asthma and eosinophilic bronchitis research

In Vitro

GW 766994 is a specific chemokine receptor-3 (CCR3) antagonist, which has entered clinical trial for asthma and eosinophilic bronchitis. GW 766994 (10 μM) reverses CCL11-induced activation of CDK5, phosphorylations of CDK5, GSK3β, and increased phosphorylation of tau in hippocampal neurons. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:CCR3 7.86 (pKi)