Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G125821-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $67.90 | |
G125821-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $109.90 | |
G125821-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $229.90 | |
G125821-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $417.90 | |
G125821-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $585.90 |
Potent, selective PPARγ agonist
Synonyms | GW 1929 | GW1929 - CAS 196808-24-9 | NCGC00015475-01 | UNII-4G86N0SVV3 | GTPL2703 | HMS1443A19 | BDBM50085048 | GW1929 | GW-1929 | SR-01000076210 | AKOS000282926 | Q27077937 | SR-01000076210-5 | DTXSID9043803 | (S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(methy |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Description: IC50 Value: 5.0±0.7 mumol/l [1]. GW1929 is a synthetic peroxisome proliferator-activated receptor-γ (PPARγ) agonist, in vitro: Using Ba2+ (10 mmol/l) as the charge carrier through VDCC, the half-inhibition co |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of Peroxisome proliferator-activated receptor-γ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (2S)-2-(2-benzoylanilino)-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]propanoic acid |
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INCHI | InChI=1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18,27,32H,19-21H2,1H3,(H,35,36)/t27-/m0/s1 |
InChi Key | QTQMRBZOBKYXCG-MHZLTWQESA-N |
Canonical SMILES | CN(CCOC1=CC=C(C=C1)CC(C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4 |
Isomeric SMILES | CN(CCOC1=CC=C(C=C1)C[C@@H](C(=O)O)NC2=CC=CC=C2C(=O)C3=CC=CC=C3)C4=CC=CC=N4 |
PubChem CID | 6518171 |
Molecular Weight | 495.57 |
PubChem CID | 6518171 |
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ChEMBL Ligand | CHEMBL434063 |
BindingDB Ligand | 50085048 |
CAS Registry No. | 196808-24-9 |
NURSA Ligand | 10.1621/ZGND9Z39K3 |
RCSB PDB Ligand | EDK |
Enter Lot Number to search for COA:
Solubility | 25°C: DMSO |
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Sensitivity | Light sensitive |
1. Degrelle SA et al.. (2017) New Transcriptional Reporters to Quantify and Monitor PPAR?Activity.. PPAR Res, 2017 (6139107). [PMID:29225614] |
2. Shoaito H et al.. (2019) The Role of Peroxisome Proliferator–Activated Receptor Gamma (PPAR?) in Mono(2-ethylhexyl) Phthalate (MEHP)-Mediated Cytotrophoblast Differentiation.. Environ Health Perspect, 127 (2): (27003). [PMID:30810372] |