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GW7647 - 98%, high purity , CAS No.265129-71-3, Agonist of Peroxisome proliferator-activated receptor-α

  • Moligand™
  • ≥98%
Item Number
G274812
Grouped product items
SKUSizeAvailabilityPrice Qty
G274812-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$129.90
G274812-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$195.90
G274812-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$338.90
G274812-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$587.90
G274812-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$848.90
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Highly potent, selective PPARα agonist

View related series
Peroxisome proliferator-activated receptor-α Agonist

Basic Description

SynonymsGW7647|265129-71-3|GW 7647|GW-7647|2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid|2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-methylpropanoic acid|NTL2A9CAZ7|CHE
Specifications & Purity98%
Storage TempStore at -20°C
Shipped InDry ice
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of Peroxisome proliferator-activated receptor-α
Product Description

Application：

GW7647 is a potent PPARα agonist, with EC50s of 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ and PPARδ, respectively.


Associated Targets

PPARA Tclin Peroxisome proliferator-activated receptor alpha 25 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 2-[4-[2-[4-cyclohexylbutyl(cyclohexylcarbamoyl)amino]ethyl]phenyl]sulfanyl-2-methylpropanoic acid
INCHI InChI=1S/C29H46N2O3S/c1-29(2,27(32)33)35-26-18-16-24(17-19-26)20-22-31(28(34)30-25-14-7-4-8-15-25)21-10-9-13-23-11-5-3-6-12-23/h16-19,23,25H,3-15,20-22H2,1-2H3,(H,30,34)(H,32,33)
InChi Key PKNYXWMTHFMHKD-UHFFFAOYSA-N
Canonical SMILES CC(C)(C(=O)O)SC1=CC=C(C=C1)CCN(CCCCC2CCCCC2)C(=O)NC3CCCCC3
Isomeric SMILES CC(C)(C(=O)O)SC1=CC=C(C=C1)CCN(CCCCC2CCCCC2)C(=O)NC3CCCCC3
WGK Germany 3
PubChem CID 3392731
Molecular Weight 502.75

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
B2320152Certificate of AnalysisDec 13, 2023 G274812
B2320234Certificate of AnalysisDec 13, 2023 G274812
B2320318Certificate of AnalysisDec 13, 2023 G274812
B2320345Certificate of AnalysisDec 13, 2023 G274812
B2320353Certificate of AnalysisDec 13, 2023 G274812

Chemical and Physical Properties

SolubilitySoluble in DMSO to 25 mM and in ethanol to 100 mM；insoluble in water

Safety and Hazards(GHS)

WGK Germany 3
RIDADR NONHforallmodesoftransport

Related Documents

 SDS

 Specification Sheet

References

1. Kang Y et al..  (2016)  A role of CB1R in inducing ?-rhythm coordination between the gustatory and gastrointestinal insula..  Sci Rep,  6  (32529).  [PMID:27581068]

Solution Calculators

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