GW7647 - 98%, high purity , CAS No.265129-71-3, Agonist of Peroxisome proliferator-activated receptor-α

Item Number

G274812

• Synonyms: GW7647 - CAS 265129-71-3 | 2-((4-(2-(1-cyclohexylbutyl)-3-cyclohexylureido)ethyl)phenylthio)-2-methylpropionic acid | NCGC00015480-07 | AKOS024456744 | DTXSID1040748 | 2-[[4-[2-[[(cyclohexylamino)carbonyl](4-cyclohexylbutyl)amino]ethyl]phenyl]thio]-2-meth
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: GW7647 reduces serum triglyceride levels and increases hepatic expression of β-oxidation-related genes. GW7647 combined with metformin can increase the levels of serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in the setting of h
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of Peroxisome proliferator-activated receptor-α
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Application：

GW7647 is a potent PPARα agonist, with EC50s of 6 nM, 1.1 μM, and 6.2 μM for human PPARα, PPARγ and PPARδ, respectively.