GW9508 - ≥98%, high purity , CAS No.885101-89-3, Agonist of FFA1 receptor;Agonist of FFA4 receptor

Item Number

G126253

• Synonyms: GW9508|885101-89-3|3-(4-((3-Phenoxybenzyl)amino)phenyl)propanoic acid|GW-9508|GW 9508|3-(4-(3-phenoxybenzylamino)phenyl)propanoic acid|4T77GYP2CS|4-[[(3-Phenoxyphenyl)methyl]amino]benzenepropanoic acid|CHEMBL207881|3-(4-{[(3-phenoxyphenyl)methyl]amino}phe
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: GW 9508 is a cell-permeable aminophenylpropanoate that acts as a potent and selective agonist for the G-protein coupled receptor (GPCR) GRP40/FFA1 receptor (EC50 ～50 nM) with reduced activity towards family members GRP120 (EC50 ～3.5 μM), GRP41/GRP43 (EC50
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of FFA1 receptor;Agonist of FFA4 receptor
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

GW9508 is a potent and selective agonist for FFA1 (GPR40) with pEC50 of 7.32, 100-fold selective against GPR120, stimulates insulin secretion in a glucose-sensitive manner.
An aminophenylpropanoate agonist at the GRP40/FFA1 receptor.