Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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G288281-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $56.90 | |
G288281-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $199.90 | |
G288281-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $312.90 | |
G288281-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $623.90 | |
G288281-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $999.90 |
Potent and selective Nav1.7 blocker; analgesic
Specifications & Purity | ≥98%(HPLC) |
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Biochemical and Physiological Mechanisms | Potent and selective Nav1.7 blocker (IC50= 3.2 nM). Exhibits 10x selectivity for Nav1.7 over Nav1.1, Nav1.2, and Nav1.6 channels. Displays prolonged residency time on the Nav1.7 channel. Chronic dosing increases compound potency ~10-fold and provides effi |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
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IUPAC Name | 4-[[1-[[2-chloro-5-(trifluoromethyl)phenyl]methyl]piperidin-4-yl]methoxy]-5-cyclopropyl-2-fluoro-N-methylsulfonylbenzamide |
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INCHI | InChI=1S/C25H27ClF4N2O4S/c1-37(34,35)31-24(33)20-11-19(16-2-3-16)23(12-22(20)27)36-14-15-6-8-32(9-7-15)13-17-10-18(25(28,29)30)4-5-21(17)26/h4-5,10-12,15-16H,2-3,6-9,13-14H2,1H3,(H,31,33) |
InChi Key | KYBPOTYVFWNSGS-UHFFFAOYSA-N |
Canonical SMILES | CS(=O)(=O)NC(=O)C1=C(C=C(C(=C1)C2CC2)OCC3CCN(CC3)CC4=C(C=CC(=C4)C(F)(F)F)Cl)F |
Isomeric SMILES | CS(=O)(=O)NC(=O)C1=C(C=C(C(=C1)C2CC2)OCC3CCN(CC3)CC4=C(C=CC(=C4)C(F)(F)F)Cl)F |
PubChem CID | 118120545 |
Molecular Weight | 563 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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C2419148 | Certificate of Analysis | Jan 29, 2024 | G288281 |
C2419149 | Certificate of Analysis | Jan 29, 2024 | G288281 |
C2419150 | Certificate of Analysis | Jan 29, 2024 | G288281 |
C2419151 | Certificate of Analysis | Jan 29, 2024 | G288281 |
C2419152 | Certificate of Analysis | Jan 29, 2024 | G288281 |
C2419153 | Certificate of Analysis | Jan 29, 2024 | G288281 |
C2419155 | Certificate of Analysis | Jan 29, 2024 | G288281 |
C2419156 | Certificate of Analysis | Jan 29, 2024 | G288281 |
C2419157 | Certificate of Analysis | Jan 29, 2024 | G288281 |
C2419158 | Certificate of Analysis | Jan 29, 2024 | G288281 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 56.3, Max Conc. mM: 100 |
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