HA155 - ≥98.0%, high purity , CAS No.1312201-00-5

Item Number

H647467

Grouped product items
SKU	Size	Availability	Price	Qty
H647467-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$150.90
H647467-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$450.90

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Basic Description

Synonyms	B-[4-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronic acid \| Boronic acid, B-[4-[[4-[(Z)-[3-[(4-fluorophenyl)Methyl]-2,4-dioxo-5-thiazolidinylidene]Methyl]phenoxy]Methyl]phenyl]- \| Boronic acid, B-[4-[[
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	HA-155 is a potent and selective autotaxin (ATX) inhibitor with an IC 50 of 5.7 nM.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	HA-155 is a potent and selective autotaxin (ATX) inhibitor with an IC 50 of 5.7 nM In Vitro HA-155 inhibits ATX by binding to the ATX active site. HA155 completely attenuates the thrombin-mediated increase in platelet-derived LPA in a dose-dependent manner. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 5.7 nM (ATX)

Associated Targets(Human)

ENPP2 Tchem Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (2 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ENPP2 Tchem Autotaxin (2645 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	[4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid
INCHI	InChI=1S/C24H19BFNO5S/c26-20-9-3-17(4-10-20)14-27-23(28)22(33-24(27)29)13-16-5-11-21(12-6-16)32-15-18-1-7-19(8-2-18)25(30)31/h1-13,30-31H,14-15H2/b22-13-
InChi Key	BRWUZCBSWABPMR-XKZIYDEJSA-N
Canonical SMILES	B(C1=CC=C(C=C1)COC2=CC=C(C=C2)C=C3C(=O)N(C(=O)S3)CC4=CC=C(C=C4)F)(O)O
Isomeric SMILES	B(C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C\3/C(=O)N(C(=O)S3)CC4=CC=C(C=C4)F)(O)O
PubChem CID	46856189
Molecular Weight	463.29

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Basic Description