Halopemide - 97%, high purity , CAS No.59831-65-1

Item Number

H334673

• Synonyms: Halopemide | 59831-65-1 | R 34,301 | R-34301 | NSC-354856 | MLS003171133 | 65Q28TV0ZY | CHEMBL245621 | N-(2-(4-(5-Chloro-2-oxo-1-benzimidazolinyl)piperidino)ethyl)-p-fluorobenzamide | Halopemida | Halopemidum | Benzamide, N-(2-(4-(5-chloro-2,3-dihydro-2-oxo-1H-benzimidazol-1-y
• Specifications & Purity: ≥97%
• Biochemical and Physiological Mechanisms: Halopemide is a dopamine receptor antagonist and a phospholipase D2 inhibitor. Halopemide may be used as a screen to identify inhibitors of human PLD2 using an in vitro biochemical assay. It is also inhibitory at benzodiazepine binding sites.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

Halopemide is a dopamine inhibitor and a PC-PLD2 (phospholipase D2) inhibitor. Halopemide may be used as a screen to identify inhibitors of human PLD2 using an in vitro biochemical assay. It is also inhibitory at benzodiazepine binding sites. Halopemide is an inhibitor of PC-PLD1 (PLD1).

Application：

Halopemide, a non-specific phospholipase D (PLD) antagonist, may be used with selective PLD antagonists (CAY10593, a PLD1 antagonist; CAY10594 or ML298, selective PLD2 antagonist) to help define the role and physiological effects regulated by phospholipase D enzymes. Halopemide may be used as the basis of the design and development of more selective PLD antagonists.