Grouped product items

SKU

Size

Availability

Price

Qty

H345402-100mg

100mg

Available within 4-8 weeks(?)

$38.90

H345402-500mg

500mg

Available within 4-8 weeks(?)

$95.90

H345402-1g

In stock

$171.90

H345402-5g

In stock

$769.90

Basic Description

Synonyms	BH175460 \| NCGC00094972-01 \| NCGC00094972-02 \| NSC 640470 \| HMS1921N14 \| 1-Methyl-2,9-dihydro-7H-pyrido[3,4-b]indol-7-one--hydrogen chloride (1/1) \| CCG-38714 \| FT-0626862 \| 9H-PYRIDO(3,4-B)INDOL-7-OL, 1-METHYL-, HYDROCHLORIDE (1:1) \| EINECS 254-980-1 \| H
Specifications & Purity	≥97%
Storage Temp	Protected from light,Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Product Description	Harmol Hydrochloride induces apoptosis by Caspase-8 activation.

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (18204 Activities)

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GLA Tclin Alpha-galactosidase A (5444 Activities)

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GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

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CASP1 Tchem Caspase-1 (6235 Activities)

Discover Target: CASP1

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CASP7 Tchem Caspase-7 (3146 Activities)

Discover Target: CASP7

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

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A498 (42825 Activities)

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ACHN (49357 Activities)

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CAKI-1 (44928 Activities)

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CCRF-CEM (65223 Activities)

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COLO 205 (50209 Activities)

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DLD-1 (17511 Activities)

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DMS-273 (14108 Activities)

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HL-60 (67320 Activities)

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HT-29 (80576 Activities)

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K562 (73714 Activities)

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KM12 (47707 Activities)

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M14 (47487 Activities)

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MOLT-4 (49676 Activities)

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OVCAR-3 (48710 Activities)

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OVCAR-4 (44535 Activities)

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OVCAR-5 (45555 Activities)

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OVCAR-8 (47708 Activities)

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RPMI-8226 (44974 Activities)

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RXF 393 (41971 Activities)

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RXF 631 (11415 Activities)

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SF-295 (48000 Activities)

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SK-MEL-2 (46422 Activities)

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SK-MEL-28 (48833 Activities)

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SK-MEL-5 (47095 Activities)

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SK-OV-3 (52876 Activities)

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SN12C (47755 Activities)

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SNB-19 (46794 Activities)

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SNB-78 (14240 Activities)

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TK-10 (45540 Activities)

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U-251 (51189 Activities)

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UACC-257 (46019 Activities)

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UACC-62 (47335 Activities)

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UO-31 (46270 Activities)

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XF498 (12972 Activities)

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786-0 (47912 Activities)

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A549 (127892 Activities)

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EKVX (44102 Activities)

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NCI-H322M (45589 Activities)

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HCC 2998 (41480 Activities)

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HCT-116 (91556 Activities)

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HOP-18 (11577 Activities)

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HOP-92 (41141 Activities)

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NCI-H460 (60772 Activities)

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Associated Targets(non-human)

Cruzipain (33337 Activities)

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CHO (4503 Activities)

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GCN5 Histone acetyltransferase GCN5 (89 Activities)

Discover Target: GCN5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BCHE Cholinesterase (8742 Activities)

Discover Target: BCHE

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Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FTL Ferritin light chain (43324 Activities)

Discover Target: FTL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one;hydrochloride
INCHI	InChI=1S/C12H10N2O.ClH/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12;/h2-6,13-14H,1H3;1H
InChi Key	RBOUBJPHXSVUTH-UHFFFAOYSA-N
Canonical SMILES	CC1=C2C(=C3C=CC(=O)C=C3N2)C=CN1.Cl
Isomeric SMILES	CC1=C2C(=C3C=CC(=O)C=C3N2)C=CN1.Cl
RTECS	UV1048000
PubChem CID	94507
Molecular Weight	234.68

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
I2224299	Certificate of Analysis	Jul 18, 2022	H345402
I2224300	Certificate of Analysis	Jul 18, 2022	H345402
I2224301	Certificate of Analysis	Jul 18, 2022	H345402
I2224302	Certificate of Analysis	Jul 18, 2022	H345402
I2224318	Certificate of Analysis	Jul 18, 2022	H345402
L2402222	Certificate of Analysis	Jul 18, 2022	H345402

Chemical and Physical Properties

Sensitivity	light sensitive
Refractive Index	n20D~1.79 (Predicted)

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help.
RTECS	UV1048000

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Harmol Hydrochloride - 97%, high purity , CAS No.40580-83-4

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

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SKU	Size	Availability	Price
H345402-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$38.90
H345402-500mg	500mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$95.90
H345402-1g	1g	In stock	$171.90
H345402-5g	5g	In stock	$769.90