Basic Description

Product Name	Hck Mouse mAb - Primary antibody, specific to Hck, Mouse IgG1
Synonyms	AIPCV\|p59Hck\|p61Hck\|Bmk\|EC 2.7.10\|EC 2.7.10.2\|Hck\|Hctk\|hemopoietic cell kinaseJTK9\|JTK9\|p59-HCK/p60-HCK\|tyrosine-protein kinase HCK\|Bmk antibody\|Hck 1 antibody\|Hck antibody\|HCK_HUMAN antibody\|Hemopoietic cell kinase antibody\|JTK9 antibody\|p59-HCK/p60-HCK
Specifications & Purity	ExactAb™, Validated, Carrier Free, High performance, 0.5 mg/mL
Host species	Mouse
Specificity	Hck
Immunogen	Recombinant human HCK expressed in E.coli (AA 1-526).
Positive Control	WB: THP-1 and Hep G2 cell lysates. ICC/IF: Hep G2 cells.
Conjugation	Unconjugated
Grade	Carrier Free, ExactAb™, High performance, Validated
Product Description	Mouse anti Human Hck Antibody, Monoclonal (1508CT602.13.1), could be used for WB, ICC, IF and so on. Application WB: 1/2000-1/4000 ICC/IF: 1/25 Protein Function May serve as part of a signaling pathway coupling the Fc receptor to the activation of the respiratory burst. May also contribute to neutrophil migration and may regulate the degranulation process of neutrophils.

Product Properties

Isotype	Mouse IgG1
Light Chain Type	kappa
SDS-PAGE	150 kDa
Purification Method	Protein G purified
Form	Liquid
Concentration	0.5 mg/mL
Storage Temp	Store at -20°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Hck Mouse mAb (Ab106982) - Western Blot
All lanes: Hck Mouse mAb (Ab106982) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab138040) at 1/30000 dilution

Predicted band size: 60 kDa
Observed band size: 58 kDa
Exposure time: 10.0 s

Hck Mouse mAb (Ab106982) - IF/ICC
Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized Hep G2 (human liver hepatocellular carcinoma cell line) cells labeling HCK with Hck Mouse mAb (Ab106982) at 1/25 dilution,
followed by Dylight® 488-conjugated goat anti-mouse IgG secondary antibody at 1/200 dilution (green). Immunofluorescence image showing cytoplasm staining on HepG2 cell line. Cytoplasmic actin is detected with Dylight® 554 Phalloidin at 1/100 dilution (red). The nuclear counter stain is DAPI (blue).

Associated Targets

HCK Tclin Tyrosine-protein kinase HCK 0 Activities

Discover Target: HCK

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Application

Application	Dilution info
ICC/IF	1:25
WB	1/2000-1/4000
WB	1/2000-1/4000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0303024	Certificate of Analysis	Mar 08, 2024	Ab106982
ZJ24F0303023	Certificate of Analysis	Mar 08, 2024	Ab106982

References

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Hck Mouse mAb - Primary antibody, specific to Hck, Mouse IgG1