HCV-796 (Nesbuvir) - ≥98%, high purity , Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor, CAS No.691852-58-1, Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor

  • ≥98%
Item Number
N127338
Grouped product items
SKUSizeAvailabilityPrice Qty
N127338-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$350.90
N127338-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$486.90
N127338-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,095.90

Basic Description

SynonymsPB24322 | SCHEMBL2513096 | BDBM50454876 | PB42775 | 5-Cyclopropyl-2-(4-fluorophenyl)-6-((2-hydroxyethyl)(methylsulfonyl)amino)-N-methyl-1-benzofuran-3-carboxamide | F84824 | 5-cyclopropyl-2-(4-fluorophenyl)-6-[(2-hydroxyethyl)(methylsulfonyl)amino]-N-meth
Specifications & Purity≥98%
Biochemical and Physiological Mechanisms

Nesbuvir, a novel selective nonstructural protein 5B (NS5B) polymerase inhibitor, act as candidate for HCV treatment.

Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeINHIBITOR
Mechanism of actionHepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor

Product Properties

ALogP2.7

Associated Targets(Human)

Huh-7 (12904 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS5B Hepatitis C virus NS5B RNA-dependent RNA polymerase (3026 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hepatitis C virus (23859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NS5A Nonstructural protein 5A (2812 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 5-cyclopropyl-2-(4-fluorophenyl)-6-[2-hydroxyethyl(methylsulfonyl)amino]-N-methyl-1-benzofuran-3-carboxamide
INCHI InChI=1S/C22H23FN2O5S/c1-24-22(27)20-17-11-16(13-3-4-13)18(25(9-10-26)31(2,28)29)12-19(17)30-21(20)14-5-7-15(23)8-6-14/h5-8,11-13,26H,3-4,9-10H2,1-2H3,(H,24,27)
InChi Key WTDWVLJJJOTABN-UHFFFAOYSA-N
Canonical SMILES CNC(=O)C1=C(OC2=CC(=C(C=C21)C3CC3)N(CCO)S(=O)(=O)C)C4=CC=C(C=C4)F
Isomeric SMILES CNC(=O)C1=C(OC2=CC(=C(C=C21)C3CC3)N(CCO)S(=O)(=O)C)C4=CC=C(C=C4)F
PubChem CID 11561383
Molecular Weight 446.49

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO mg/mL Water mg/mL Ethanol mg/mL

Related Documents

Solution Calculators