HDAC8-IN-1 - 10mM in DMSO, high purity , CAS No.1417997-93-3(DMSO)

  • 10mM in DMSO
Item Number
H655008
Grouped product items
SKUSizeAvailabilityPrice Qty
H655008-1ml
1ml
Available within 8-12 weeks(?)
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$145.90

Basic Description

Specifications & Purity10mM in DMSO
Biochemical and Physiological MechanismsHDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM.

In Vitro

HDAC8-IN-1 is a HDAC8 inhibitor with an IC 50 of 27.2 nM in cancer cell lines. HDAC8-IN-1 (compound 22 d) shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5); HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

IC50& Target:HDAC8 27.2 nM (IC 50 )

Associated Targets(Human)

HDAC8 Tclin Histone deacetylase 8 (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES COC1=CC(=C(C=C1)C=CC(=O)NO)C2=CC=C(C=C2)C3=CC=CC=C3
Molecular Weight 345.39

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