Skip to the beginning of the images gallery

heme , CAS No.14875-96-8, Agonist of Rev-Erb-α;Agonist of Rev-Erb-β

9 Citations

Moligand™

CAS#: 14875-96-8
Formula: C₃₄H₃₂FeN₄O₄²
Molecular Weight: 616.49
PubChem CID: 26945

Item Number

H610806

Grouped product items
SKU	Size	Availability	Price	Qty
H610806-25μg	25μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
H610806-100μg	100μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,334.90

View related series

Rev-Erb-α Agonist Rev-Erb-β Agonist

Basic Description

Synonyms	heme \| protoheme \| heme b \| 14875-96-8 \| ferroprotoporphyrin \| Ferroheme \| Reduced hematin \| Haem \| protoheme IX \| Iron protoporphyrin ix \| hematin \| Protohaem \| Ferrous protoheme \| Iron protoporphyrin \| Ferrous protoheme IX \| Ferroprotoporphyrin IX \| 42VZT0U6YR \| Iron(II) protoporphyrin
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of Rev-Erb-α;Agonist of Rev-Erb-β

Associated Targets(Human)

NR1D1 Tchem Nuclear receptor subfamily 1 group D member 1 (0 Activities)

Discover Target: NR1D1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1D2 Tchem Nuclear receptor subfamily 1 group D member 2 (1 Activities)

Discover Target: NR1D2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid;iron(2+)
INCHI	InChI=1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+2/p-2
InChi Key	KABFMIBPWCXCRK-UHFFFAOYSA-L
Canonical SMILES	CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Fe+2]
Isomeric SMILES	CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=N4)C=C5C(=C(C(=N5)C=C1[N-]2)C)C=C)C)C=C)C)CCC(=O)O)CCC(=O)O.[Fe+2]
PubChem CID	26945
Molecular Weight	616.49

CAS Registry No.

Wikipedia

ChEBI

PubChem CID

Citations of This Product

1. Yuxiang Zhou, Yanyun Wang, Mengyuan Song, Lanrui Jiang, Chaoran Sun, Shuangshuang Wang, Hewen Yao, Zefei Wang, Xindi Wang, Chunhui Liu, Haibo Luo, Feng Song. (2024) A high-throughput droplet digital PCR system aiming eight DNA methylation targets for age prediction. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 240 (115943). [PMID:38181558]
2. Meng Shi, Demin Kong, Hui Zhang, Deming Rao, Tianlong Zhao, Jing Yang, Zhanzhi Liu, Sheng Chen, Fengshan Zhang, Jing Wu, Lei Wang. (2024) Enhancing the heterologous expression of latex clearing protein from Streptomyces sp. strain K30 in Escherichia coli through fermentation condition optimization and molecular modification. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 254 (127995). [PMID:37949282]
3. Tao Zhan, Xiao-Zhen Feng, Yun-Yun Cheng, Guo-Cheng Han, Zhencheng Chen, Heinz-Bernhard Kraatz. (2023) Electrochemical sensor for ultrasensitive sensing of biotin based on heme conjugated with gold nanoparticles and its electrooxidation mechanism. FOOD CHEMISTRY, 429 (136997). [PMID:37516051]
4. Guo-Cheng Han, Jiating Hou, Zong-Li Huang, Xiao-Zhen Feng, Zhencheng Chen, Wenxiang Xiao, Shuang Li. (2017) Electrochemical Behaviors of Ferrocene Dicarboxylate and its Application for Heme Detection. International Journal of Electrochemical Science, 12 (6245). [PMID:]
5. Linlin Gao, Lin Zhang, Huan Liu, Jielun Hu. (2023) In vitro gastrointestinal digestion of whole grain noodles supplemented with soluble dietary fiber and their effects on children fecal microbiota. Food Bioscience, 53 (102600). [PMID:]
6. Qi Yang, Huan Yu, Yiling Qu, Xiaochun Zhang, Ruocheng Xia, Ziwei Wang, Rui Tan, Lei Xiong, Shihan Xi, Jun Wu, Yuzhen Gao, Suhua Zhang, Chengtao Li. (2022) Developmental validation of the novel six-dye GoldeneyeTM DNA ID System 35InDel kit for forensic application. Forensic Sciences Research, [PMID:36817233]
7. Xueting Guan, Yujing Feng, Yunyao Jiang, Yeye Hu, Ji Zhang, Zhengpeng Li, Chao Song, Fu Li, Jincai Hou, Ting Shen, Weicheng Hu. (2022) Simulated digestion and in vitro fermentation of a polysaccharide from lotus (Nelumbo nucifera Gaertn.) root residue by the human gut microbiota. FOOD RESEARCH INTERNATIONAL, 155 (111074). [PMID:35400452]
8. Jin-Guang Liu, Jia-Zheng Wan, Qing-Min Lin, Guo-Cheng Han, Xiao-Zhen Feng, Zhencheng Chen. (2021) Convenient Heme Nanorod Modified Electrode for Quercetin Sensing by Two Common Electrochemical Methods. Micromachines, 12 (12): (1519). [PMID:34945369]
9. Huaxu Zhou, Xinyu Ma, Ajabkhan Sailjoi, Yanqi Zou, Xingyu Lin, Fei Yan, Bin Su, Jiyang Liu. (2022) Vertical silica nanochannels supported by nanocarbon composite for simultaneous detection of serotonin and melatonin in biological fluids. SENSORS AND ACTUATORS B-CHEMICAL, 353 (131101). [PMID:]

References

1. Yuxiang Zhou, Yanyun Wang, Mengyuan Song, Lanrui Jiang, Chaoran Sun, Shuangshuang Wang, Hewen Yao, Zefei Wang, Xindi Wang, Chunhui Liu, Haibo Luo, Feng Song. (2024) A high-throughput droplet digital PCR system aiming eight DNA methylation targets for age prediction. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 240 (115943). [PMID:38181558]
2. Meng Shi, Demin Kong, Hui Zhang, Deming Rao, Tianlong Zhao, Jing Yang, Zhanzhi Liu, Sheng Chen, Fengshan Zhang, Jing Wu, Lei Wang. (2024) Enhancing the heterologous expression of latex clearing protein from Streptomyces sp. strain K30 in Escherichia coli through fermentation condition optimization and molecular modification. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 254 (127995). [PMID:37949282]
3. Tao Zhan, Xiao-Zhen Feng, Yun-Yun Cheng, Guo-Cheng Han, Zhencheng Chen, Heinz-Bernhard Kraatz. (2023) Electrochemical sensor for ultrasensitive sensing of biotin based on heme conjugated with gold nanoparticles and its electrooxidation mechanism. FOOD CHEMISTRY, 429 (136997). [PMID:37516051]
4. Guo-Cheng Han, Jiating Hou, Zong-Li Huang, Xiao-Zhen Feng, Zhencheng Chen, Wenxiang Xiao, Shuang Li. (2017) Electrochemical Behaviors of Ferrocene Dicarboxylate and its Application for Heme Detection. International Journal of Electrochemical Science, 12 (6245). [PMID:]
5. Linlin Gao, Lin Zhang, Huan Liu, Jielun Hu. (2023) In vitro gastrointestinal digestion of whole grain noodles supplemented with soluble dietary fiber and their effects on children fecal microbiota. Food Bioscience, 53 (102600). [PMID:]
6. Qi Yang, Huan Yu, Yiling Qu, Xiaochun Zhang, Ruocheng Xia, Ziwei Wang, Rui Tan, Lei Xiong, Shihan Xi, Jun Wu, Yuzhen Gao, Suhua Zhang, Chengtao Li. (2022) Developmental validation of the novel six-dye GoldeneyeTM DNA ID System 35InDel kit for forensic application. Forensic Sciences Research, [PMID:36817233]
7. Xueting Guan, Yujing Feng, Yunyao Jiang, Yeye Hu, Ji Zhang, Zhengpeng Li, Chao Song, Fu Li, Jincai Hou, Ting Shen, Weicheng Hu. (2022) Simulated digestion and in vitro fermentation of a polysaccharide from lotus (Nelumbo nucifera Gaertn.) root residue by the human gut microbiota. FOOD RESEARCH INTERNATIONAL, 155 (111074). [PMID:35400452]
8. Jin-Guang Liu, Jia-Zheng Wan, Qing-Min Lin, Guo-Cheng Han, Xiao-Zhen Feng, Zhencheng Chen. (2021) Convenient Heme Nanorod Modified Electrode for Quercetin Sensing by Two Common Electrochemical Methods. Micromachines, 12 (12): (1519). [PMID:34945369]
9. Huaxu Zhou, Xinyu Ma, Ajabkhan Sailjoi, Yanqi Zou, Xingyu Lin, Fei Yan, Bin Su, Jiyang Liu. (2022) Vertical silica nanochannels supported by nanocarbon composite for simultaneous detection of serotonin and melatonin in biological fluids. SENSORS AND ACTUATORS B-CHEMICAL, 353 (131101). [PMID:]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

heme , CAS No.14875-96-8, Agonist of Rev-Erb-α;Agonist of Rev-Erb-β

Basic Description

Associated Targets(Human)

Names and Identifiers

Database links

Certificates

Certificate of Analysis(COA)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator