Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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H105438-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $38.90 |
Synonyms | (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside | CHEBI:28775 | DIOSVEIN | EINECS 208-288-1 | Hesperetin 7 Rhamnoglucoside | Q385937 | D01038 | hesperidin | DTXSID9 |
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Specifications & Purity | analytical standard |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Grade | analytical standard |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one |
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INCHI | InChI=1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1 |
InChi Key | QUQPHWDTPGMPEX-QJBIFVCTSA-N |
Canonical SMILES | COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2 |
Isomeric SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O |
WGK Germany | 3 |
Molecular Weight | 610.56 |
Beilstein | 75140 |
Enter Lot Number to search for COA:
Sensitivity | Air sensitive |
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Melt Point(°C) | 250-255°C |
WGK Germany | 3 |
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Merck Index | 4671 |
1. Min-Rui Tai, Hong-Wu Ji, Jian-Ping Chen, Xiao-Fei Liu, Bing-Bing Song, Sai-Yi Zhong, Aaqil Rifai, David R. Nisbet, Colin J. Barrow, Richard J. Williams, Rui Li. (2023) Biomimetic triumvirate nanogel complexes via peptide-polysaccharide-polyphenol self-assembly. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 251 (126232). [PMID:37562478] [10.1016/j.ijbiomac.2023.126232] |
2. Hong-Qi Xia, Wanbing Chen, Diyang Qiu, Jiwu Zeng. (2023) Portable Microelectrochemical Sensors for Rapid and Sensitive Determination of Hesperidin in Citrus reticulate ‘Chachi’ Peel. MOLECULES, 28 (14): (5316). [PMID:37513189] [10.3390/molecules28145316] |
3. Xiao-Hua Zhang, Xiang-Dong Qing, Jing-Jing Zheng, Yan Yu, Jiaojiao Huang, Chao Kang, Zhi Liu. (2023) Aqueous two-phase systems coupled with chemometrics-enhanced HPLC-DAD for simultaneous extraction and determination of flavonoids in honey. Food Chemistry-X, 19 (100766). [PMID:37780266] [10.1016/j.fochx.2023.100766] |
4. Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning. (2023) Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol–Feeding Mice. Nutrients, 15 (5): (1078). [PMID:36904078] [10.3390/nu15051078] |
5. Pan Lixia, Ye Hangyu, Pi Xionge, Liu Wei, Wang Zhao, Zhang Yinjun, Zheng Jianyong. (2023) Effects of several flavonoids on human gut microbiota and its metabolism by in vitro simulated fermentation. Frontiers in Microbiology, 14 [PMID:36819019] [10.3389/fmicb.2023.1092729] |
6. Hong-qi Xia, Diyang Qiu, Wanbing Chen, Genlin Mao, Jiwu Zeng. (2023) In situ formed and fully integrated laser-induced graphene electrochemical chips for rapid and simultaneous determination of bioflavonoids in citrus fruits. MICROCHEMICAL JOURNAL, 188 (108474). [PMID:] [10.1016/j.microc.2023.108474] |
7. Chun Xiao Li, Fu Rong Wang, Bing Zhang, Ze Yuan Deng, Hong Yan Li. (2023) Stability and antioxidant activity of phenolic compounds during in vitro digestion. JOURNAL OF FOOD SCIENCE, 88 (2): (696-716). [PMID:36617678] [10.1111/1750-3841.16440] |
8. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2023) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). [PMID:36484340] [10.1039/D2FO02233H] |
9. Yu Bo, Luo Shiyu, Ding Yuhan, Gong Zijie, Nie Ting. (2022) Insights into glycosidic bond specificity of an engineered selective α-L-rhamnosidase N12-Rha via activity assays and molecular modelling. AMB Express, 12 (1): (1-14). [PMID:36370155] [10.1186/s13568-022-01489-5] |
10. Dan Yu, Fei Liu, Changdong Zou, Xiao Yang. (2023) Municipal green waste promotes iron release from steelmaking slag in water. RESOURCES CONSERVATION AND RECYCLING, 188 (106722). [PMID:] [10.1016/j.resconrec.2022.106722] |
11. Qi Quan, Wei Liu, Jiajing Guo, Meiling Ye, Juhua Zhang. (2022) Effect of Six Lactic Acid Bacteria Strains on Physicochemical Characteristics, Antioxidant Activities and Sensory Properties of Fermented Orange Juices. Foods, 11 (13): (1920). [PMID:35804736] [10.3390/foods11131920] |
12. Ye Hangyu, Li Xiaojun, Li Luyuan, Zhang Yinjun, Zheng Jianyong. (2022) Homologous Expression and Characterization of α-L-rhamnosidase from Aspergillus niger for the Transformation of Flavonoids. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 194 (8): (3453-3467). [PMID:35366188] [10.1007/s12010-022-03894-9] |
13. Hong-qi Xia, Tingting Gu, Ruiyi Fan, Jiwu Zeng. (2022) Comparative investigation of bioflavonoid electrocatalysis in 1D, 2D, and 3D carbon nanomaterials for simultaneous detection of naringin and hesperidin in fruits. RSC Advances, 12 (11): (6409-6415). [PMID:35424592] [10.1039/D1RA07217J] |
14. Xiangrong Li, Ruonan Xu, Zeqing Cheng, Zhizhi Song, Ziyang Wang, Hanxiao Duan, Xinzhe Wu, Tianjun Ni. (2021) Comparative study on the interaction between flavonoids with different core structures and hyaluronidase. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 262 (120079). [PMID:34175762] [10.1016/j.saa.2021.120079] |
15. Dan-Hua He, Yu-Fei Chen, Yi-Le Zhou, Shi-Bing Zhang, Ming Hong, Xianjun Yu, Su-Fen Wei, Xiang-Zhen Fan, Si-Yi Li, Qi Wang, Yongzhi Lu, Yong-Qiang Liu. (2021) Phytochemical library screening reveals betulinic acid as a novel Skp2-SCF E3 ligase inhibitor in non–small cell lung cancer. CANCER SCIENCE, 112 (8): (3218-3232). [PMID:34080260] [10.1111/cas.15005] |
16. Lingrong Wen, Mingyang He, Chunxiao Yin, Yueming Jiang, Donghui Luo, Bao Yang. (2021) Phenolics in Citrus aurantium fruit identified by UHPLC-MS/MS and their bioactivities. LWT-FOOD SCIENCE AND TECHNOLOGY, 147 (111671). [PMID:] [10.1016/j.lwt.2021.111671] |
17. Zhang Xiao-Hua, Ma Yi-Xin, Yi Chong, Qing Xiang-Dong, Liu Zhi, Zheng Jing-Jing, Lin Fang, Lv Tian-Feng. (2020) Chemometrics-enhanced HPLC–DAD as a rapid and interference-free strategy for simultaneous quantitative analysis of flavonoids in Chinese propolis. EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 246 (10): (1909-1918). [PMID:] [10.1007/s00217-020-03543-7] |
18. Hui Guo, Yunfei Chen, Na Song, Xinyi Yang, Shen Yao, Junqing Qian. (2020) Screening of lipase inhibitors from bamboo leaves based on the magnetic ligand fishing combined with HPLC/MS. MICROCHEMICAL JOURNAL, 153 (104497). [PMID:] [10.1016/j.microc.2019.104497] |
19. Xinlin Chen, Shang Xue, Yaolan Lin, Jianguang Luo, Lingyi Kong. (2020) Immobilization of porcine pancreatic lipase onto a metal-organic framework, PPL@MOF: A new platform for efficient ligand discovery from natural herbs. ANALYTICA CHIMICA ACTA, 1099 (94). [PMID:31986282] [10.1016/j.aca.2019.11.042] |
20. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu. (2019) Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies. Foods, 8 (9): (355). [PMID:31438605] [10.3390/foods8090355] |
21. Xuexue Feng, Tielei Wu, Bingqing Yu, Yan Wang, Shian Zhong. (2017) Hydrophilic surface molecularly imprinted naringin prepared via reverse atom transfer radical polymerization with excellent recognition ability in a pure aqueous phase. RSC Advances, 7 (45): (28082-28091). [PMID:] [10.1039/C7RA00202E] |
22. Songbai Liu, Yuanqing Fu, Si Nian. (2014) Buffering colour fluctuation of purple sweet potato anthocyanins to acidity variation by surfactants. FOOD CHEMISTRY, 162 (16). [PMID:24874351] [10.1016/j.foodchem.2014.04.029] |
23. Shi Shen,Jingbo Wang,Qin Zhuo,Xi Chen,Tingting Liu,Shuang-Qing Zhang. (2018-05-09) Quantitative and Discriminative Evaluation of Contents of Phenolic and Flavonoid and Antioxidant Competence for Chinese Honeys from Different Botanical Origins.. Molecules (Basel, Switzerland), 23 ((5)): [PMID:29738446] |
1. Min-Rui Tai, Hong-Wu Ji, Jian-Ping Chen, Xiao-Fei Liu, Bing-Bing Song, Sai-Yi Zhong, Aaqil Rifai, David R. Nisbet, Colin J. Barrow, Richard J. Williams, Rui Li. (2023) Biomimetic triumvirate nanogel complexes via peptide-polysaccharide-polyphenol self-assembly. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 251 (126232). [PMID:37562478] [10.1016/j.ijbiomac.2023.126232] |
2. Hong-Qi Xia, Wanbing Chen, Diyang Qiu, Jiwu Zeng. (2023) Portable Microelectrochemical Sensors for Rapid and Sensitive Determination of Hesperidin in Citrus reticulate ‘Chachi’ Peel. MOLECULES, 28 (14): (5316). [PMID:37513189] [10.3390/molecules28145316] |
3. Xiao-Hua Zhang, Xiang-Dong Qing, Jing-Jing Zheng, Yan Yu, Jiaojiao Huang, Chao Kang, Zhi Liu. (2023) Aqueous two-phase systems coupled with chemometrics-enhanced HPLC-DAD for simultaneous extraction and determination of flavonoids in honey. Food Chemistry-X, 19 (100766). [PMID:37780266] [10.1016/j.fochx.2023.100766] |
4. Shengxiang Yi, Gaowei Zhang, Mingyan Liu, Wenjie Yu, Guohua Cheng, Liping Luo, Fangjian Ning. (2023) Citrus Honey Ameliorates Liver Disease and Restores Gut Microbiota in Alcohol–Feeding Mice. Nutrients, 15 (5): (1078). [PMID:36904078] [10.3390/nu15051078] |
5. Pan Lixia, Ye Hangyu, Pi Xionge, Liu Wei, Wang Zhao, Zhang Yinjun, Zheng Jianyong. (2023) Effects of several flavonoids on human gut microbiota and its metabolism by in vitro simulated fermentation. Frontiers in Microbiology, 14 [PMID:36819019] [10.3389/fmicb.2023.1092729] |
6. Hong-qi Xia, Diyang Qiu, Wanbing Chen, Genlin Mao, Jiwu Zeng. (2023) In situ formed and fully integrated laser-induced graphene electrochemical chips for rapid and simultaneous determination of bioflavonoids in citrus fruits. MICROCHEMICAL JOURNAL, 188 (108474). [PMID:] [10.1016/j.microc.2023.108474] |
7. Chun Xiao Li, Fu Rong Wang, Bing Zhang, Ze Yuan Deng, Hong Yan Li. (2023) Stability and antioxidant activity of phenolic compounds during in vitro digestion. JOURNAL OF FOOD SCIENCE, 88 (2): (696-716). [PMID:36617678] [10.1111/1750-3841.16440] |
8. Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo. (2023) Chemical composition and anti-inflammatory activities of Castanopsis honey. Food & Function, 14 (1): (250-261). [PMID:36484340] [10.1039/D2FO02233H] |
9. Yu Bo, Luo Shiyu, Ding Yuhan, Gong Zijie, Nie Ting. (2022) Insights into glycosidic bond specificity of an engineered selective α-L-rhamnosidase N12-Rha via activity assays and molecular modelling. AMB Express, 12 (1): (1-14). [PMID:36370155] [10.1186/s13568-022-01489-5] |
10. Dan Yu, Fei Liu, Changdong Zou, Xiao Yang. (2023) Municipal green waste promotes iron release from steelmaking slag in water. RESOURCES CONSERVATION AND RECYCLING, 188 (106722). [PMID:] [10.1016/j.resconrec.2022.106722] |
11. Qi Quan, Wei Liu, Jiajing Guo, Meiling Ye, Juhua Zhang. (2022) Effect of Six Lactic Acid Bacteria Strains on Physicochemical Characteristics, Antioxidant Activities and Sensory Properties of Fermented Orange Juices. Foods, 11 (13): (1920). [PMID:35804736] [10.3390/foods11131920] |
12. Ye Hangyu, Li Xiaojun, Li Luyuan, Zhang Yinjun, Zheng Jianyong. (2022) Homologous Expression and Characterization of α-L-rhamnosidase from Aspergillus niger for the Transformation of Flavonoids. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 194 (8): (3453-3467). [PMID:35366188] [10.1007/s12010-022-03894-9] |
13. Hong-qi Xia, Tingting Gu, Ruiyi Fan, Jiwu Zeng. (2022) Comparative investigation of bioflavonoid electrocatalysis in 1D, 2D, and 3D carbon nanomaterials for simultaneous detection of naringin and hesperidin in fruits. RSC Advances, 12 (11): (6409-6415). [PMID:35424592] [10.1039/D1RA07217J] |
14. Xiangrong Li, Ruonan Xu, Zeqing Cheng, Zhizhi Song, Ziyang Wang, Hanxiao Duan, Xinzhe Wu, Tianjun Ni. (2021) Comparative study on the interaction between flavonoids with different core structures and hyaluronidase. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 262 (120079). [PMID:34175762] [10.1016/j.saa.2021.120079] |
15. Dan-Hua He, Yu-Fei Chen, Yi-Le Zhou, Shi-Bing Zhang, Ming Hong, Xianjun Yu, Su-Fen Wei, Xiang-Zhen Fan, Si-Yi Li, Qi Wang, Yongzhi Lu, Yong-Qiang Liu. (2021) Phytochemical library screening reveals betulinic acid as a novel Skp2-SCF E3 ligase inhibitor in non–small cell lung cancer. CANCER SCIENCE, 112 (8): (3218-3232). [PMID:34080260] [10.1111/cas.15005] |
16. Lingrong Wen, Mingyang He, Chunxiao Yin, Yueming Jiang, Donghui Luo, Bao Yang. (2021) Phenolics in Citrus aurantium fruit identified by UHPLC-MS/MS and their bioactivities. LWT-FOOD SCIENCE AND TECHNOLOGY, 147 (111671). [PMID:] [10.1016/j.lwt.2021.111671] |
17. Zhang Xiao-Hua, Ma Yi-Xin, Yi Chong, Qing Xiang-Dong, Liu Zhi, Zheng Jing-Jing, Lin Fang, Lv Tian-Feng. (2020) Chemometrics-enhanced HPLC–DAD as a rapid and interference-free strategy for simultaneous quantitative analysis of flavonoids in Chinese propolis. EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 246 (10): (1909-1918). [PMID:] [10.1007/s00217-020-03543-7] |
18. Hui Guo, Yunfei Chen, Na Song, Xinyi Yang, Shen Yao, Junqing Qian. (2020) Screening of lipase inhibitors from bamboo leaves based on the magnetic ligand fishing combined with HPLC/MS. MICROCHEMICAL JOURNAL, 153 (104497). [PMID:] [10.1016/j.microc.2019.104497] |
19. Xinlin Chen, Shang Xue, Yaolan Lin, Jianguang Luo, Lingyi Kong. (2020) Immobilization of porcine pancreatic lipase onto a metal-organic framework, PPL@MOF: A new platform for efficient ligand discovery from natural herbs. ANALYTICA CHIMICA ACTA, 1099 (94). [PMID:31986282] [10.1016/j.aca.2019.11.042] |
20. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu. (2019) Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies. Foods, 8 (9): (355). [PMID:31438605] [10.3390/foods8090355] |
21. Xuexue Feng, Tielei Wu, Bingqing Yu, Yan Wang, Shian Zhong. (2017) Hydrophilic surface molecularly imprinted naringin prepared via reverse atom transfer radical polymerization with excellent recognition ability in a pure aqueous phase. RSC Advances, 7 (45): (28082-28091). [PMID:] [10.1039/C7RA00202E] |
22. Songbai Liu, Yuanqing Fu, Si Nian. (2014) Buffering colour fluctuation of purple sweet potato anthocyanins to acidity variation by surfactants. FOOD CHEMISTRY, 162 (16). [PMID:24874351] [10.1016/j.foodchem.2014.04.029] |
23. Shi Shen,Jingbo Wang,Qin Zhuo,Xi Chen,Tingting Liu,Shuang-Qing Zhang. (2018-05-09) Quantitative and Discriminative Evaluation of Contents of Phenolic and Flavonoid and Antioxidant Competence for Chinese Honeys from Different Botanical Origins.. Molecules (Basel, Switzerland), 23 ((5)): [PMID:29738446] |