Hexahydrocurcumin , CAS No.36062-05-2

  • ≥99%
Item Number
H351682
Grouped product items
SKUSizeAvailabilityPrice Qty
H351682-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$115.90
H351682-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$282.90
H351682-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$417.90
H351682-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$691.90
H351682-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$937.90

Basic Description

Synonyms5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-3-heptanone | 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptan-3-one
Specifications & Purity≥99%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Hexahydrocurcumin is one of the major metabolites of curcumin and a selective, orally active COX-2 inhibitor. Hexahydrocurcumin is inactive against COX-1. Hexahydrocurcumin has antioxidant, anticancer and anti-inflammatory activities.

Associated Targets(Human)

DNMT1 Tclin DNA (cytosine-5)-methyltransferase 1 (978 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BACE1 Tchem Beta-secretase 1 (15641 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania major (2877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania mexicana (936 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RBL-2H3 (1162 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)heptan-3-one
INCHI InChI=1S/C21H26O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,16,22,24-25H,3-4,7-8,13H2,1-2H3
InChi Key RSAHICAPUYTWHW-UHFFFAOYSA-N
Canonical SMILES COC1=C(C=CC(=C1)CCC(CC(=O)CCC2=CC(=C(C=C2)O)OC)O)O
Isomeric SMILES COC1=C(C=CC(=C1)CCC(CC(=O)CCC2=CC(=C(C=C2)O)OC)O)O
PubChem CID 5318039
Molecular Weight 374.43

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
C2419173Certificate of AnalysisJan 25, 2024 H351682
C2419174Certificate of AnalysisJan 25, 2024 H351682
C2419175Certificate of AnalysisJan 25, 2024 H351682
C2419176Certificate of AnalysisJan 25, 2024 H351682
C2419177Certificate of AnalysisJan 25, 2024 H351682
C2419178Certificate of AnalysisJan 25, 2024 H351682
C2419179Certificate of AnalysisJan 25, 2024 H351682
C2419180Certificate of AnalysisJan 25, 2024 H351682
C2419181Certificate of AnalysisJan 25, 2024 H351682
C2419183Certificate of AnalysisJan 25, 2024 H351682

Chemical and Physical Properties

SolubilityDMSO: 45 mg/mL (120.19 mM), Need ultrasonic

Related Documents

Citations of This Product

1. Dan Yuan, Qi Li, Qibo Zhang, Feibai Zhou, Qiangzhong Zhao, Mouming Zhao.  (2024)  Enhanced curcumin transportation across epithelial barrier by mucus-permeable soy protein nanoparticles-mediated dual transcytosis pathways.  FOOD CHEMISTRY,  437  (137771).  [PMID:37897825] [10.1016/j.foodchem.2023.137771]

References

1. Dan Yuan, Qi Li, Qibo Zhang, Feibai Zhou, Qiangzhong Zhao, Mouming Zhao.  (2024)  Enhanced curcumin transportation across epithelial barrier by mucus-permeable soy protein nanoparticles-mediated dual transcytosis pathways.  FOOD CHEMISTRY,  437  (137771).  [PMID:37897825] [10.1016/j.foodchem.2023.137771]

Solution Calculators