Hexamethonium bromide , CAS No.55-97-0

1 Citations
Item Number
H170991
Grouped product items
SKUSizeAvailabilityPrice Qty
H170991-5g
5g
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$58.90
H170991-25g
25g
In stock
$265.90
H170991-100g
100g
In stock
$955.90
H170991-500g
500g
In stock
$4,301.90

Antagonist at α 3 -containing nAChR

Basic Description

SynonymsHEXAMETHONIUM BROMIDE | 55-97-0 | Simpatoblock | Hexamethonium dibromide | Gangliostat | Hexamethionium bromide | Bistrium bromide | Hexamethonium (Bromide) | Esametina | Hexameton | Vegolysen | Vegolysin | Hexonium dibromide | 1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, dibr
Biochemical and Physiological MechanismsGanglionic blocker; antagonist at α 3 -containing nicotinic acetylcholine receptors (autonomic ganglia).
Storage TempArgon charged
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

ERG Tbio Transcriptional regulator ERG (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GMNN Tbio Geminin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KMT2A Tchem Histone-lysine N-methyltransferase 2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TXNRD1 Tclin Thioredoxin reductase 1, cytoplasmic (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SNCA Tchem Alpha-synuclein (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
POLI Tchem DNA polymerase iota (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PMP22 Tbio Peripheral myelin protein 22 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRND Tclin Acetylcholine receptor subunit delta (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
POLI Tchem DNA polymerase iota (116820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SNCA Tchem Alpha-synuclein (10960 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ERG Tbio Transcriptional regulator ERG (5589 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNA1 Acetylcholine receptor (120 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488179964
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179964
IUPAC Name trimethyl-[6-(trimethylazaniumyl)hexyl]azanium;dibromide
INCHI InChI=1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
InChi Key FAPSXSAPXXJTOU-UHFFFAOYSA-L
Canonical SMILES C[N+](C)(C)CCCCCC[N+](C)(C)C.[Br-].[Br-]
Isomeric SMILES C[N+](C)(C)CCCCCC[N+](C)(C)C.[Br-].[Br-]
WGK Germany 2
RTECS BQ8575000
PubChem CID 5938
Molecular Weight 362.19

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

20 results found

Lot NumberCertificate TypeDateItem
I2102234Certificate of AnalysisJun 17, 2024 H170991
A2404714Certificate of AnalysisDec 21, 2023 H170991
A2404715Certificate of AnalysisDec 21, 2023 H170991
A2404717Certificate of AnalysisDec 21, 2023 H170991
A2404718Certificate of AnalysisDec 21, 2023 H170991
A2404719Certificate of AnalysisDec 21, 2023 H170991
A2404720Certificate of AnalysisDec 21, 2023 H170991
K2005145Certificate of AnalysisSep 04, 2023 H170991
L2202429Certificate of AnalysisNov 21, 2022 H170991
A2329039Certificate of AnalysisNov 21, 2022 H170991
L2201174Certificate of AnalysisNov 21, 2022 H170991
L2201164Certificate of AnalysisNov 21, 2022 H170991
L2201163Certificate of AnalysisNov 21, 2022 H170991
L2201159Certificate of AnalysisNov 21, 2022 H170991
K2301108Certificate of AnalysisNov 21, 2022 H170991
D23142480Certificate of AnalysisNov 21, 2022 H170991
D23142469Certificate of AnalysisNov 21, 2022 H170991
B2217065Certificate of AnalysisFeb 19, 2022 H170991
I2102236Certificate of AnalysisAug 27, 2021 H170991
B2217087Certificate of AnalysisAug 27, 2021 H170991

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Chemical and Physical Properties

SolubilitySoluble in water; Soluble in Alcohol; Insoluble in Ether,Acetone,Chloroform
SensitivityHygroscopic
Melt Point(°C)282-285℃

Safety and Hazards(GHS)

Pictogram(s) GHS08
Signal Danger
Hazard Statements

H370:Causes damage to organs

Precautionary Statements

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P270:Do not eat, drink or smoke when using this product.

P308+P316:IF exposed or concerned: Get emergency medical help immediately.

WGK Germany 2
RTECS BQ8575000
Merck Index 4688

Related Documents

Citations of This Product

1. Chao Ma, Xiaona Liu, Yang Hong, Nana Yan, Chenyang Nie, Jing Wang, Peng Guo, Zhongmin Liu.  (2023)  Fluoride- and Seed-Free Synthesis of Pure-Silica Zeolite Adsorbent and Matrix Using OSDA-Mismatch Approach.  Journal of the American Chemical Society,  145  (44): (24191–24201).  [PMID:37877469]

References

1. Chao Ma, Xiaona Liu, Yang Hong, Nana Yan, Chenyang Nie, Jing Wang, Peng Guo, Zhongmin Liu.  (2023)  Fluoride- and Seed-Free Synthesis of Pure-Silica Zeolite Adsorbent and Matrix Using OSDA-Mismatch Approach.  Journal of the American Chemical Society,  145  (44): (24191–24201).  [PMID:37877469]

Solution Calculators