Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | Hippuric acid | 495-69-2 | 2-Benzamidoacetic acid | N-Benzoylglycine | Benzoylglycine | Glycine, N-benzoyl- | Benzamidoacetic acid | Benzoylaminoacetic acid | hippurate | Hippursaeure | Phenylcarbonylaminoacetic acid | Benzamidoessigsaeure | Benzoylaminoessigsaeure | N-Benzoyl-gly |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
Associated Targets(Human)
DHFR Tclin Dihydrofolate reductase (0 Activities)
SLC22A6 Tclin Solute carrier family 22 member 6 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
RUNX1 Tbio Runt-related transcription factor 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
ABCB1 Tchem Multidrug resistance protein 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
SLC22A8 Tclin Solute carrier family 22 member 8 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
KYNU Tchem Kynureninase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
LMNA Tbio Prelamin-A/C (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
AKR1B1 Tclin Aldose reductase (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
DHFR Tclin Dihydrofolate reductase (3072 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
AKR1B1 Tclin Aldose reductase (1404 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KYNU Tchem Kynureninase (42 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
LMNA Tbio Prelamin-A/C (36751 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SLC22A8 Tclin Solute carrier family 22 member 8 (241 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
Abcb1b P-glycoprotein 1 (174 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Hdac6 Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HD1 Histone deacetylase (38 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Plasmodium falciparum (966862 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Rattus norvegicus (775804 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
rep Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Slc22a20 Solute carrier family 22 member 20 (86 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Slc22a6 Solute carrier family 22 member 6 (141 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 2-benzamidoacetic acid |
|---|---|
| INCHI | InChI=1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12) |
| InChi Key | QIAFMBKCNZACKA-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC=C(C=C1)C(=O)NCC(=O)O |
| Isomeric SMILES | C1=CC=C(C=C1)C(=O)NCC(=O)O |
| WGK Germany | 3 |
| RTECS | MR8150000 |
| PubChem CID | 464 |
| Molecular Weight | 179.17 |
| Beilstein | 1073987 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Sensitivity | Moisture sensitive. |
|---|---|
| Melt Point(°C) | 188-191°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS05, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H315:Causes skin irritation H335:May cause respiratory irritation H302:Harmful if swallowed H318:Causes serious eye damage |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| RTECS | MR8150000 |
| Merck Index | 4716 |
Related Documents
Citations of This Product
| 1. Shuai Zhang, Mei Deng, Ruifen Zhang, Xuchao Jia, Fei Huang, Dong Zhao, Lihong Dong, Jianwei Chi, Zhida Sun, Qin Ma, Mingwei Zhang. (2023) Modulation effect of black rice dietary fiber on the metabolism and fermentation of cyanidin-3-glucoside in an in vitro human colonic model. Food & Function, 14 (14): (6707-6717). [PMID:37404037] [10.1039/D3FO00955F] |
| 2. Wei Jia, Xin Wang. (2023) 3-Chloropropane-1,2-diol exposure adversely influenced the bio-accessibility signatures of digested infant foods by suppressing the destabilization of α-lactalbumin and d-aspartate oxidase in a dose-dependent manner. FOOD CHEMISTRY, 427 (136729). [PMID:37385056] [10.1016/j.foodchem.2023.136729] |
| 3. Qi Liu, Shan Shao, Jingyu Bao, Syed Jalil Shah, Shumin Yue, Xinqi Luan, Qing Liu, Linguang Xing, Zhongfeng Shi, Zhenxia Zhao, Zhongxing Zhao. (2023) High accuracy prediction of dipeptide angiotensin-converting enzyme (ACE) inhibitory activity by improving the credibility of the 3D-quantitative structure-activity relationship (3D-QSAR) model database and investigating inhibition mechanism. PROCESS BIOCHEMISTRY, 131 (114). [PMID:] [10.1016/j.procbio.2023.06.010] |
| 4. Chenhui Gu, Xuewen Hu, Baixi Shan, Xiaojing Wu, Jun Chen. (2023) Targeted and non-targeted metabolomics uncovering the effects of Er-Miao-Wan formula on rats with hyperuricemia. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 226 (115246). [PMID:36731256] [10.1016/j.jpba.2023.115246] |
| 5. Xueyan Gou, Fenglin Ran, Jinru Yang, Yanrong Ma, Xin’an Wu. (2022) Construction and Evaluation of a Novel Organic Anion Transporter 1/3 CRISPR/Cas9 Double-Knockout Rat Model. Pharmaceutics, 14 (11): (2307). [PMID:36365126] [10.3390/pharmaceutics14112307] |
| 6. Zeng Sen, Hou Yaqi, Zhou Yaming, Zhou Xi, Ye Shefang, Wang Miao, Ren Lei. (2022) Adsorptive removal of uremic toxins using Zr-based MOFs for potential hemodialysis membranes. JOURNAL OF MATERIALS SCIENCE, 57 (4): (2909-2923). [PMID:] [10.1007/s10853-021-06783-4] |
| 7. Haipeng Ye, Ji Shao, Yanpeng Shi, Siwei Tan, Kewen Su, Ling Zhang, Xiaoyue Shan. (2021) Magnetic molecularly imprinted polymers for extraction of S-phenylmercapturic acid from urine samples followed by high-performance liquid chromatography. JOURNAL OF MOLECULAR RECOGNITION, 34 (11): (e2930). [PMID:34432338] [10.1002/jmr.2930] |
| 8. Junjie Yu, Junjie Wu, Dewei Xie, Lei Du, Ya-Jie Tang, Jingli Xie, Dongzhi Wei. (2020) Characterization and rational design for substrate specificity of a prolyl endopeptidase from Stenotrophomonas maltophilia. ENZYME AND MICROBIAL TECHNOLOGY, 138 (109548). [PMID:32527522] [10.1016/j.enzmictec.2020.109548] |
| 9. Bo Chen, Jie Zhou, Qilu Meng, Yang Zhang, Shihua Zhang, Liang Zhang. (2018) Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols. Food & Function, 9 (9): (4858-4864). [PMID:30156246] [10.1039/C8FO00609A] |
| 10. De-Chun Zhang, Dou Ma, Xia Li. (2017) Multiple modulator-induced syntheses, crystal structures, and luminescent properties on hippuric acid and bovine serum albumin of Ln(III) complexes with 2,2′-oxybis(benzoic acid). JOURNAL OF COORDINATION CHEMISTRY, [PMID:] [10.1080/00958972.2017.1381881] |
| 11. Chunyan Qi, Guimei Lin, Rong Zhang, Wenjuan Wu. (2017) Studies on the Bioactivities of ACE-inhibitory Peptides with Phenylalanine C-terminus Using 3D-QSAR, Molecular Docking and in vitro Evaluation. Molecular Informatics, 36 (9): (1600157). [PMID:28452129] [10.1002/minf.201600157] |
| 12. Xue-jia Zhai, Fen Chen, Chao-ran Zhu, Yong-ning Lu. (2015) A simple LC-MS/MS method for quantitative analysis of underivatized neurotransmitters in rats urine: assay development, validation and application in the CUMS rat model. BIOMEDICAL CHROMATOGRAPHY, 29 (11): (1737-1743). [PMID:25944269] [10.1002/bmc.3487] |
| 13. Tiesheng Hu, Zhipeng Li, Tingting Wang, Heping Zeng. (2015) Synthesis and Properties of Photochromic Diarylethenes Bearing Thiazole Moiety. JOURNAL OF HETEROCYCLIC CHEMISTRY, 53 (1): (109-116). [PMID:] [10.1002/jhet.2037] |
References
| 1. Shuai Zhang, Mei Deng, Ruifen Zhang, Xuchao Jia, Fei Huang, Dong Zhao, Lihong Dong, Jianwei Chi, Zhida Sun, Qin Ma, Mingwei Zhang. (2023) Modulation effect of black rice dietary fiber on the metabolism and fermentation of cyanidin-3-glucoside in an in vitro human colonic model. Food & Function, 14 (14): (6707-6717). [PMID:37404037] [10.1039/D3FO00955F] |
| 2. Wei Jia, Xin Wang. (2023) 3-Chloropropane-1,2-diol exposure adversely influenced the bio-accessibility signatures of digested infant foods by suppressing the destabilization of α-lactalbumin and d-aspartate oxidase in a dose-dependent manner. FOOD CHEMISTRY, 427 (136729). [PMID:37385056] [10.1016/j.foodchem.2023.136729] |
| 3. Qi Liu, Shan Shao, Jingyu Bao, Syed Jalil Shah, Shumin Yue, Xinqi Luan, Qing Liu, Linguang Xing, Zhongfeng Shi, Zhenxia Zhao, Zhongxing Zhao. (2023) High accuracy prediction of dipeptide angiotensin-converting enzyme (ACE) inhibitory activity by improving the credibility of the 3D-quantitative structure-activity relationship (3D-QSAR) model database and investigating inhibition mechanism. PROCESS BIOCHEMISTRY, 131 (114). [PMID:] [10.1016/j.procbio.2023.06.010] |
| 4. Chenhui Gu, Xuewen Hu, Baixi Shan, Xiaojing Wu, Jun Chen. (2023) Targeted and non-targeted metabolomics uncovering the effects of Er-Miao-Wan formula on rats with hyperuricemia. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 226 (115246). [PMID:36731256] [10.1016/j.jpba.2023.115246] |
| 5. Xueyan Gou, Fenglin Ran, Jinru Yang, Yanrong Ma, Xin’an Wu. (2022) Construction and Evaluation of a Novel Organic Anion Transporter 1/3 CRISPR/Cas9 Double-Knockout Rat Model. Pharmaceutics, 14 (11): (2307). [PMID:36365126] [10.3390/pharmaceutics14112307] |
| 6. Zeng Sen, Hou Yaqi, Zhou Yaming, Zhou Xi, Ye Shefang, Wang Miao, Ren Lei. (2022) Adsorptive removal of uremic toxins using Zr-based MOFs for potential hemodialysis membranes. JOURNAL OF MATERIALS SCIENCE, 57 (4): (2909-2923). [PMID:] [10.1007/s10853-021-06783-4] |
| 7. Haipeng Ye, Ji Shao, Yanpeng Shi, Siwei Tan, Kewen Su, Ling Zhang, Xiaoyue Shan. (2021) Magnetic molecularly imprinted polymers for extraction of S-phenylmercapturic acid from urine samples followed by high-performance liquid chromatography. JOURNAL OF MOLECULAR RECOGNITION, 34 (11): (e2930). [PMID:34432338] [10.1002/jmr.2930] |
| 8. Junjie Yu, Junjie Wu, Dewei Xie, Lei Du, Ya-Jie Tang, Jingli Xie, Dongzhi Wei. (2020) Characterization and rational design for substrate specificity of a prolyl endopeptidase from Stenotrophomonas maltophilia. ENZYME AND MICROBIAL TECHNOLOGY, 138 (109548). [PMID:32527522] [10.1016/j.enzmictec.2020.109548] |
| 9. Bo Chen, Jie Zhou, Qilu Meng, Yang Zhang, Shihua Zhang, Liang Zhang. (2018) Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols. Food & Function, 9 (9): (4858-4864). [PMID:30156246] [10.1039/C8FO00609A] |
| 10. De-Chun Zhang, Dou Ma, Xia Li. (2017) Multiple modulator-induced syntheses, crystal structures, and luminescent properties on hippuric acid and bovine serum albumin of Ln(III) complexes with 2,2′-oxybis(benzoic acid). JOURNAL OF COORDINATION CHEMISTRY, [PMID:] [10.1080/00958972.2017.1381881] |
| 11. Chunyan Qi, Guimei Lin, Rong Zhang, Wenjuan Wu. (2017) Studies on the Bioactivities of ACE-inhibitory Peptides with Phenylalanine C-terminus Using 3D-QSAR, Molecular Docking and in vitro Evaluation. Molecular Informatics, 36 (9): (1600157). [PMID:28452129] [10.1002/minf.201600157] |
| 12. Xue-jia Zhai, Fen Chen, Chao-ran Zhu, Yong-ning Lu. (2015) A simple LC-MS/MS method for quantitative analysis of underivatized neurotransmitters in rats urine: assay development, validation and application in the CUMS rat model. BIOMEDICAL CHROMATOGRAPHY, 29 (11): (1737-1743). [PMID:25944269] [10.1002/bmc.3487] |
| 13. Tiesheng Hu, Zhipeng Li, Tingting Wang, Heping Zeng. (2015) Synthesis and Properties of Photochromic Diarylethenes Bearing Thiazole Moiety. JOURNAL OF HETEROCYCLIC CHEMISTRY, 53 (1): (109-116). [PMID:] [10.1002/jhet.2037] |