Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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H111796-250mg | 250mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $25.90 | |
H111796-1g | 1g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $79.90 | |
H111796-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $260.90 |
Potent vasodilator and endogenous histamine receptor agonist.
Synonyms | 2-Imidazol-4-ylethylamine | 1H-Imidazole-4-ethanamine | 2-(1H-imidazol-5-yl)ethanamine | 2-(4-Imidazolyl)ethylamine |
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Specifications & Purity | Moligand™, ≥96% |
Biochemical and Physiological Mechanisms | Histamine, Free Base is a potent vasodilator found in normal tissues and blood. This compound is formed by the decarboxylation of L-histidine and activates NOS (nitric oxide synthase), resulting in the release of nitric oxide. Activation of Histamine H1 R |
Storage Temp | Protected from light,Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Action Type | ACTIVATOR, AGONIST |
Mechanism of action | Activator of carbonic anhydrase 1;Activator of carbonic anhydrase 5A;Activator of carbonic anhydrase 7;Agonist of H 1 receptor;Agonist of H 2 receptor;Agonist of H 3 receptor;Agonist of H 4 receptor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | A compound that activates NOS which results in the release of NO. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 2-(1H-imidazol-5-yl)ethanamine |
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INCHI | InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8) |
InChi Key | NTYJJOPFIAHURM-UHFFFAOYSA-N |
Canonical SMILES | C1=C(NC=N1)CCN |
Isomeric SMILES | C1=C(NC=N1)CCN |
WGK Germany | 3 |
RTECS | MS1050000 |
PubChem CID | 774 |
UN Number | 2811 |
Molecular Weight | 111.15 |
Beilstein | 2012 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
K2412351 | Certificate of Analysis | Nov 02, 2024 | H111796 |
K2412350 | Certificate of Analysis | Nov 02, 2024 | H111796 |
K2412349 | Certificate of Analysis | Nov 02, 2024 | H111796 |
G2431209 | Certificate of Analysis | Jun 07, 2024 | H111796 |
G2431210 | Certificate of Analysis | Jun 07, 2024 | H111796 |
G2431229 | Certificate of Analysis | Jun 07, 2024 | H111796 |
G2431230 | Certificate of Analysis | Jun 07, 2024 | H111796 |
G2431232 | Certificate of Analysis | Jun 07, 2024 | H111796 |
J2428258 | Certificate of Analysis | Jun 07, 2024 | H111796 |
E2422359 | Certificate of Analysis | Apr 20, 2024 | H111796 |
E2422360 | Certificate of Analysis | Apr 20, 2024 | H111796 |
E2422361 | Certificate of Analysis | Apr 20, 2024 | H111796 |
L2312028 | Certificate of Analysis | Jun 29, 2022 | H111796 |
A2431199 | Certificate of Analysis | Jun 29, 2022 | H111796 |
I2224334 | Certificate of Analysis | Jun 29, 2022 | H111796 |
I2224315 | Certificate of Analysis | Jun 29, 2022 | H111796 |
G2311063 | Certificate of Analysis | Jun 29, 2022 | H111796 |
C2219632 | Certificate of Analysis | Feb 14, 2022 | H111796 |
C2219557 | Certificate of Analysis | Feb 14, 2022 | H111796 |
Solubility | Soluble in water, alcohol, and hot chloroform. |
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Sensitivity | Hygroscopic & Heat & Air & Light sensitive |
Boil Point(°C) | 167°C |
Melt Point(°C) | 83-84°C |
Pictogram(s) | GHS06, GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P284:[In case of inadequate ventilation] Wear respiratory protection. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
WGK Germany | 3 |
RTECS | MS1050000 |
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33. Huang Lin, Wang Lin, Hu Xiaomeng, Chen Sen, Tao Yunwen, Su Haiyang, Yang Jing, Xu Wei, Vedarethinam Vadanasundari, Wu Shu, Liu Bin, Wan Xinze, Lou Jiatao, Wang Qian, Qian Kun. (2020) Machine learning of serum metabolic patterns encodes early-stage lung adenocarcinoma. Nature Communications, 11 (1): (1-11). [PMID:32678093] [10.1038/s41467-020-17347-6] |
34. Liu Song, Yang Huang, Marie-Jia Gou, Jacques Crommen, Zhengjin Jiang, Yifan Feng. (2020) Method development and validation for the determination of biogenic amines in soy sauce using supercritical fluid chromatography coupled with single quadrupole mass spectrometry. JOURNAL OF SEPARATION SCIENCE, 43 (13): (2728-2736). [PMID:32281256] [10.1002/jssc.202000030] |
35. Hailong Sun, Shuangping Liu, Jieqi Mao, Ziwei Yu, Zhijie Lin, Jian Mao. (2020) New insights into the impacts of huangjiu compontents on intoxication. FOOD CHEMISTRY, 317 (126420). [PMID:32101783] [10.1016/j.foodchem.2020.126420] |
36. Enming Miao, Nazhen Zhang, Shiwei Lu, Yufeng Hu, Lin Fu, Hao Zhou, Jingjing Zhan, Minghuo Wu. (2020) Solid phase “on-situ” quadraplex isotope dimethyl labeling for the analysis of biogenic amines in beers by liquid chromatography-high resolution mass spectrometry. JOURNAL OF CHROMATOGRAPHY A, 1613 (460712). [PMID:31759641] [10.1016/j.chroma.2019.460712] |
37. Chen Jia, Li Yunchun, Huang Yanni, Zhang Haijuan, Chen Xingguo, Qiu Hongdeng. (2019) Fluorometric dopamine assay based on an energy transfer system composed of aptamer-functionalized MoS2 quantum dots and MoS2 nanosheets. MICROCHIMICA ACTA, 186 (2): (1-9). [PMID:30617543] [10.1007/s00604-018-3143-5] |
38. Wang Zhong-Xia, Gao Yuan-Fei, Yu Xian-He, Kong Fen-Ying, Lv Wei-Xin, Wang Wei. (2018) Photoluminescent coral-like carbon-branched polymers as nanoprobe for fluorometric determination of captopril. MICROCHIMICA ACTA, 185 (9): (1-9). [PMID:30128634] [10.1007/s00604-018-2961-9] |
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37. Chen Jia, Li Yunchun, Huang Yanni, Zhang Haijuan, Chen Xingguo, Qiu Hongdeng. (2019) Fluorometric dopamine assay based on an energy transfer system composed of aptamer-functionalized MoS2 quantum dots and MoS2 nanosheets. MICROCHIMICA ACTA, 186 (2): (1-9). [PMID:30617543] [10.1007/s00604-018-3143-5] |
38. Wang Zhong-Xia, Gao Yuan-Fei, Yu Xian-He, Kong Fen-Ying, Lv Wei-Xin, Wang Wei. (2018) Photoluminescent coral-like carbon-branched polymers as nanoprobe for fluorometric determination of captopril. MICROCHIMICA ACTA, 185 (9): (1-9). [PMID:30128634] [10.1007/s00604-018-2961-9] |
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40. Yirui Zhao,Xue Sang,Hongshun Hao,Jingran Bi,Gongliang Zhang,Hongman Hou. (2021-02-12) Novel starter cultures Virgibacillus spp. selected from grasshopper sub shrimp paste to inhibit biogenic amines accumulation.. AMB Express, 11 ((1)): (25-25). [PMID:33569734] |