HNMPA-(AM)3 - ≥98%, high purity , CAS No.120944-03-8

Item Number

H275917

Grouped product items
SKU	Size	Availability	Price	Qty
H275917-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$197.90
H275917-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$741.90

Insulin receptor tyrosine kinase inhibitor

Basic Description

Synonyms	KBio2_003027 \| Bio1_000738 \| NCGC00163452-02 \| CBiol_001963 \| CS-0084188 \| HNMPA-(AM)3 \| KBio2_005595 \| J-004417 \| [bis(acetyloxymethoxy)phosphoryl-naphthalen-2-ylmethoxy]methyl acetate \| 3-[(acetyloxy)methoxy]-4-(naphthalen-2-yl)-3-oxido-8-oxo-2,5,7-trio
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Insulin receptor tyrosine kinase inhibitor (IC 50 = 100 μM). Inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Cell-permeable analog of HNMPA (cell impermeable analog available).
Storage Temp	Store at -20°C,Desiccated
Shipped In	Ice chest + Ice pads
Note	Unstable; make up solutions fresh and use immediately. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Shipped at 4°C. Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLA Tclin Alpha-galactosidase A (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLA Tclin Alpha-galactosidase A (5444 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	[bis(acetyloxymethoxy)phosphoryl-naphthalen-2-ylmethoxy]methyl acetate
INCHI	InChI=1S/C20H23O10P/c1-14(21)25-11-28-20(19-9-8-17-6-4-5-7-18(17)10-19)31(24,29-12-26-15(2)22)30-13-27-16(3)23/h4-10,20H,11-13H2,1-3H3
InChi Key	UQODAZKXEREJLZ-UHFFFAOYSA-N
Canonical SMILES	CC(=O)OCOC(C1=CC2=CC=CC=C2C=C1)P(=O)(OCOC(=O)C)OCOC(=O)C
Isomeric SMILES	CC(=O)OCOC(C1=CC2=CC=CC=C2C=C1)P(=O)(OCOC(=O)C)OCOC(=O)C
PubChem CID	3619
Molecular Weight	454.36

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Basic Description