Homo-PROTAC cereblon degrader 1 - 99%, high purity , CAS No.2244520-98-5

Item Number

H412807

Grouped product items
SKU	Size	Availability	Price
H412807-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$38.90
H412807-5mg	5mg	In stock	$129.90
H412807-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$178.90
H412807-25mg	25mg	In stock	$359.90
H412807-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$588.90
H412807-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,018.90

E3 Ligase Inhibitors

Basic Description

Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Homo-PROTAC cereblon degrader 1 (OUN20985) is a potent and efficient cereblon (CRBN) degrader with minimal effects on IKZF1 and IKZF3.
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	Information Homo-PROTAC cereblon degrader 1 Homo-PROTAC cereblon degrader 1 (OUN20985) is a potent and efficient cereblon (CRBN) degrader with minimal effects on IKZF1 and IKZF3. Targets CRBN

Associated Targets(Human)

CRBN Tclin Cereblon/Ikaros (139 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

VHL Tchem VHL/Cereblon (225 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	2-(2,6-dioxopiperidin-3-yl)-4-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethylamino]isoindole-1,3-dione
INCHI	InChI=1S/C32H32N6O10/c39-23-9-7-21(27(41)35-23)37-29(43)17-3-1-5-19(25(17)31(37)45)33-11-13-47-15-16-48-14-12-34-20-6-2-4-18-26(20)32(46)38(30(18)44)22-8-10-24(40)36-28(22)42/h1-6,21-22,33-34H,7-16H2,(H,35,39,41)(H,36,40,42)
InChi Key	OXIPFLHBDVDLDS-UHFFFAOYSA-N
Canonical SMILES	C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O
Isomeric SMILES	C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCOCCOCCNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O
PubChem CID	137628659
Molecular Weight	660.63

Certificates

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8 results found

Lot Number	Certificate Type	Date	Item
K2329443	Certificate of Analysis	Nov 15, 2023	H412807
K2329444	Certificate of Analysis	Nov 15, 2023	H412807
K2329445	Certificate of Analysis	Nov 15, 2023	H412807
K2329446	Certificate of Analysis	Nov 15, 2023	H412807
K2329447	Certificate of Analysis	Nov 15, 2023	H412807
K2329448	Certificate of Analysis	Nov 15, 2023	H412807
K2329449	Certificate of Analysis	Nov 15, 2023	H412807
K2329450	Certificate of Analysis	Nov 15, 2023	H412807

Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

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Basic Description