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Human angiotension Ⅱ Relative Molecular Weight - Angiotensin II:1045.5, high purity , CAS No.4474-91-3, Agonist of AT 1 receptor;Agonist of AT 2 receptor;Channel blocker of K 2P3.1

15 Citations
Item Number
A119706
Grouped product items
SKUSizeAvailabilityPrice Qty
A119706-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$125.90
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Potent vasoconstrictor peptide

View related series
AT1 receptor Agonist AT2 receptor Agonist K2P3.1 Channel blocker

Basic Description

SynonymsCHEBI:131170 | CHEBI:48432 | HB3488 | HY-13948 | ty-10721 | Angiotensin II, ile(5)- | Q27293293 | 5-L-Isoleucineangiotensin II | Angiotensin II (acetate);Ang II (acetate);DRVYIHPF (acetate) | C50H71N13O12 | Angiotensinum II | Angiotensin 2 | Angiotensin I
Specifications & PurityMoligand™, Angiotensin II:1045.5
Biochemical and Physiological MechanismsEndogenous potent vasoconstrictor peptide; endogenous substrate for ACE2. Stimulates the synthesis and release of aldosterone.
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST, CHANNEL BLOCKER
Mechanism of actionAgonist of AT 1 receptor;Agonist of AT 2 receptor;Channel blocker of K 2P3.1

Associated Targets(Human)

AGTR1 Tclin Type-1 angiotensin II receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AGTR2 Tchem Type-2 angiotensin II receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNK3 Tclin Potassium channel subfamily K member 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-3 (62116 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H295R (47 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr1b Type-1B angiotensin II receptor (525 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Angiotensin II type 1a (AT-1a) receptor (440 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr1 Type-1A angiotensin II receptor (520 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oryctolagus cuniculus (11301 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr1b Angiotensin II receptor (1735 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr1b Angiotensin II receptor (AT-1) type-1 (1480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium gallinaceum (527 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (3S)-3-amino-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[(2S)-2-[[(1S)-1-carboxy-2-phenylethyl]carbamoyl]pyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
INCHI InChI=1S/C50H71N13O12/c1-5-28(4)41(47(72)59-36(23-31-25-54-26-56-31)48(73)63-20-10-14-38(63)45(70)60-37(49(74)75)22-29-11-7-6-8-12-29)62-44(69)35(21-30-15-17-32(64)18-16-30)58-46(71)40(27(2)3)61-43(68)34(13-9-19-55-50(52)53)57-42(67)33(51)24-39(65)66/h6-8,11-12,15-18,25-28,33-38,40-41,64H,5,9-10,13-14,19-24,51H2,1-4H3,(H,54,56)(H,57,67)(H,58,71)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,65,66)(H,74,75)(H4,52,53,55)/t28-,33-,34-,35-,36-,37-,38-,40-,41-/m0/s1
InChi Key CZGUSIXMZVURDU-JZXHSEFVSA-N
Canonical SMILES CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(=O)O)N
Isomeric SMILES CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(=O)O)N
WGK Germany 3
RTECS BW2165000
PubChem CID 172198
Molecular Weight 1046.18

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
E2317410Certificate of AnalysisMay 08, 2023 A119706
C2212179Certificate of AnalysisFeb 15, 2022 A119706

Chemical and Physical Properties

SolubilitySoluble to 1 (mg/mL) in water}

Safety and Hazards(GHS)

WGK Germany 3
RTECS BW2165000

Related Documents

 SDS

 Specification Sheet

FAQs and Articles

FAQ
A New Role for Angiotensin II in Aging
Categories: Technical articles
Tags:
Alzheimer's disease Neuropeptide Angiotensin hypertensive

Citations of This Product

How to Cite Aladdin Scientific Products?
1. Wang Meng-yang, Yu Tian-xiang, Wang Qin-yan, Han Xue, Hu Xiang, Ye Shi-ju, Long Xiao-hong, Wang Yi, Zhu Hong, Luo Wu, Liang Guang.  (2023)  OTUD1 promotes hypertensive kidney fibrosis and injury by deubiquitinating CDK9 in renal epithelial cells.  ACTA PHARMACOLOGICA SINICA,    (1-12).  [PMID:38110583]
2. Jiajia Zhang, Yu Tu, Jiajia Wei, Ruyi Zheng, Ji Shao, Qinhua Chen, Guang Liang, Huazhong Ying, Xue Han, Qiaojuan Shi.  (2023)  Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE,    (26): (166911).  [PMID:37813169]
3. Yushu Liu, Dong Wang, Yimin Jin, Guifang Sun, Qi Lou, Hong Wang, Weimin Li.  (2023)  Costunolide ameliorates angiotensin II-induced atrial inflammation and fibrosis by regulating mitochondrial function and oxidative stress in mice: A possible therapeutic approach for atrial fibrillation.  MICROVASCULAR RESEARCH,    (104600).  [PMID:37666318]
4. Wang Shuai, Bai Jie, Che Yilin, Qu Weikun, Li Jing.  (2023)  Fucoidan inhibits apoptosis and improves cardiac remodeling by inhibiting p53 transcriptional activation through USP22/Sirt 1.  Frontiers in Pharmacology,  14    [PMID:37324479]
5. Fangze Huang, Ximao Liu, Junjie Liu, Yu Xie, Li Zhao, Deshen Liu, Zifeng Zeng, Xiu Liu, Shaoyi Zheng, Zezhou Xiao.  (2023)  Phosphatidylethanolamine aggravates Angiotensin II-induced atrial fibrosis by triggering ferroptosis in mice.  Frontiers in Pharmacology,  14  (1148410).  [PMID:37288112]
6. Mengyang Wang, Xue Han, Tianxiang Yu, Minxiu Wang, Wu Luo, Chunpeng Zou, Xiuyun Li, Gao Li, Gaojun Wu, Yi Wang, Guang Liang.  (2023)  OTUD1 promotes pathological cardiac remodeling and heart failure by targeting STAT3 in cardiomyocytes.  Theranostics,  13  (7): ( 2263–2280).  [PMID:37153745]
7. Tian-Lun Wen, Jia-Hui Bai, Ming-Mai Bao, Yong Qin, Yue Su, Yin-Long Guo.  (2023)  Ultrasonic sample introduction combined with flame assisted thermal ionization: Pretreatment-free direct mass spectrometry analysis for fraction collecting tubes of preparative liquid chromatography.  TALANTA,  259  (124508).  [PMID:37043878]
8. Weiwei Zhu, Minxiu Wang, Leiming Jin, Bin Yang, Bin Bai, Rumbidzai Natasha Mutsinze, Wei Zuo, Nipon Chattipakorn, Joo Young Huh, Guang Liang, Yi Wang.  (2022)  Licochalcone A protects against LPS-induced inflammation and acute lung injury by directly binding with myeloid differentiation factor 2 (MD2).  BRITISH JOURNAL OF PHARMACOLOGY,  180  (8): (1114-1131).  [PMID:36480410]
9. Siyuan Shen, Gaojun Wu, Wu Luo, Weixin Li, Xiaobo Li, Chengyi Dai, Weijian Huang, Guang Liang.  (2023)  Leonurine attenuates angiotensin II-induced cardiac injury and dysfunction via inhibiting MAPK and NF-κB pathway.  PHYTOMEDICINE,  108  (154519).  [PMID:36332391]
10. Kai-Wen Ren, Xiao-Hong Yu, Yu-Hui Gu, Xin Xie, Yu Wang, Shi-hao Wang, Hui-Hua Li, Hai-Lian Bi.  (2022)  Cardiac-specific knockdown of Bhlhe40 attenuates angiotensin II (Ang II)-Induced atrial fibrillation in mice.  Frontiers in Cardiovascular Medicine,  9  (957903).  [PMID:36304536]
11. Na Yang, Chunpeng Zou, Wu Luo, Diyun Xu, Mengyang Wang, Yi Wang, Gaojun Wu, Peiren Shan, Guang Liang.  (2022)  Sclareol attenuates angiotensin II-induced cardiac remodeling and inflammation via inhibiting MAPK signaling.  PHYTOTHERAPY RESEARCH,  37  (2): (578-591).  [PMID:36178264]
12. Yawen Deng, Zhitong Li, Xiangbo An, Rui Fan, Yao Wang, Jiatian Li, Xiaolei Yang, Jiawei Liao, Yunlong Xia.  (2022)  Hyperhomocysteinemia Promotes Cardiac Hypertrophy in Hypertension.  Oxidative Medicine and Cellular Longevity,  2022  (1486157).  [PMID:36046692]
13. Xin Xie, Ting-ting Shen, Hai-lian Bi, Zhuo-lin Su, Zi-qi Liao, Ying Zhang, Lei Shi, Yun-long Xia.  (2022)  Melatonin inhibits angiotensin II–induced atrial fibrillation through preventing degradation of Ang II Type I Receptor–Associated Protein (ATRAP).  BIOCHEMICAL PHARMACOLOGY,  202  (115146).  [PMID:35710020]
14. Mengyang Wang, Wu Luo, Tianxiang Yu, Shiqi Liang, Jinfeng Sun, Yi Zhang, Xue Han, Xiaohong Long, Guang Liang, Gao Li.  (2022)  Corynoline protects ang II-induced hypertensive heart failure by increasing PPARα and Inhibiting NF-κB pathway.  BIOMEDICINE & PHARMACOTHERAPY,  150  (113075).  [PMID:35658238]
15. Guangquan Hu, Xiaojie Ding, Feng Gao, Jiehua Li.  (2022)  Calcium and integrin binding protein 1 (CIB1) induces myocardial fibrosis in myocardial infarction via regulating the PI3K/Akt pathway.  EXPERIMENTAL ANIMALS,      [PMID:34349085]
16. Jinfu Qian, Wu Luo, Chengyi Dai, Jun Wang, Xinfu Guan, Chunpeng Zou, Nipon Chattipakorn, Gaojun Wu, Weijian Huang, Guang Liang.  (2021)  Myeloid differentiation protein 2 mediates angiotensin II-induced inflammation and mesenchymal transition in vascular endothelium.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE,  1867  (166043).  [PMID:33338595]
17. Ke Lin, Wu Luo, Jueqian Yan, Siyuan Shen, Qirui Shen, Jun Wang, Xinfu Guan, Gaojun Wu, Weijian Huang, Guang Liang.  (2021)  TLR2 regulates angiotensin II-induced vascular remodeling and EndMT through NF-κB signaling.  Aging-US,  13  (2): ( 2553–2574).  [PMID:33318302]
18. Zhengyong Wang, Yuqi Cao, Yingjie Lu, Fang Zhang, Yue Su, Yinlong Guo.  (2020)  Ultrasonic extraction and nebulization in real-time coupled with carbon fiber ionization mass spectrometry for rapid screening of the synthetic drugs adulterated into herbal products.  ANALYTICA CHIMICA ACTA,  1136  (62).  [PMID:33081950]
19. Guo Xiao, Zhang Yongtao, Lu Changhong, Qu Fengxia, Jiang Xianyan.  (2020)  Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy.  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,  84  (4): (714-724).  [PMID:31797747]
20. Rui Guo, Ningning Liu, Hao Liu, Junhua Zhang, Han Zhang, Yingchao Wang, Mirko Baruscotti, Lu Zhao, Yi Wang.  (2020)  High content screening identifies licoisoflavone A as a bioactive compound of Tongmaiyangxin Pills to restrain cardiomyocyte hypertrophy via activating Sirt3.  PHYTOMEDICINE,  68  (153171).  [PMID:32018211]
21. Jing Yang, Wenpeng Zhang, Hongjun Zhang, Minlin Zhong, Wenbo Cao, Zishuai Li, Xi Huang, Zongxiu Nie, Jiaming Liu, Peng Li, Xiaoxiao Ma, Zheng Ouyang.  (2019)  Polydopamine-Modified Substrates for High-Sensitivity Laser Desorption Ionization Mass Spectrometry Imaging.  ACS Applied Materials & Interfaces,  11  (49): (46140–46148).  [PMID:31729222]
22. Xin Xie, Hai-Lian Bi, Song Lai, Yun-Long Zhang, Nan Li, Hua-Jun Cao, Ling Han, Hong-Xia Wang, Hui-Hua Li.  (2019)  The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation.  Science Advances,  5  (5):   [PMID:31086810]
23. Zheng Xu, Chunpeng Zou, Weihui Yu, Sujing Xu, Lan Huang, Zia Khan, Jingying Wang, Guang Liang, Yi Wang.  (2019)  Inhibition of STAT3 activation mediated by toll-like receptor 4 attenuates angiotensin II-induced renal fibrosis and dysfunction.  BRITISH JOURNAL OF PHARMACOLOGY,  176  (14): (2627-2641).  [PMID:30958891]

References

1. Khanna A, English SW, Wang XS, Ham K, Tumlin J, Szerlip H, Busse LW, Altaweel L, Albertson TE, Mackey C et al..  (2017)  Angiotensin II for the Treatment of Vasodilatory Shock..  N Engl J Med,  377  (5): (419-430).  [PMID:28528561]
2. Wang Meng-yang, Yu Tian-xiang, Wang Qin-yan, Han Xue, Hu Xiang, Ye Shi-ju, Long Xiao-hong, Wang Yi, Zhu Hong, Luo Wu, Liang Guang.  (2023)  OTUD1 promotes hypertensive kidney fibrosis and injury by deubiquitinating CDK9 in renal epithelial cells.  ACTA PHARMACOLOGICA SINICA,    (1-12).  [PMID:38110583]
3. Jiajia Zhang, Yu Tu, Jiajia Wei, Ruyi Zheng, Ji Shao, Qinhua Chen, Guang Liang, Huazhong Ying, Xue Han, Qiaojuan Shi.  (2023)  Dectin1 contributes to hypertensive vascular injury by promoting macrophage infiltration through activating the Syk/NF-κB pathway.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE,    (26): (166911).  [PMID:37813169]
4. Yushu Liu, Dong Wang, Yimin Jin, Guifang Sun, Qi Lou, Hong Wang, Weimin Li.  (2023)  Costunolide ameliorates angiotensin II-induced atrial inflammation and fibrosis by regulating mitochondrial function and oxidative stress in mice: A possible therapeutic approach for atrial fibrillation.  MICROVASCULAR RESEARCH,    (104600).  [PMID:37666318]
5. Wang Shuai, Bai Jie, Che Yilin, Qu Weikun, Li Jing.  (2023)  Fucoidan inhibits apoptosis and improves cardiac remodeling by inhibiting p53 transcriptional activation through USP22/Sirt 1.  Frontiers in Pharmacology,  14    [PMID:37324479]
6. Fangze Huang, Ximao Liu, Junjie Liu, Yu Xie, Li Zhao, Deshen Liu, Zifeng Zeng, Xiu Liu, Shaoyi Zheng, Zezhou Xiao.  (2023)  Phosphatidylethanolamine aggravates Angiotensin II-induced atrial fibrosis by triggering ferroptosis in mice.  Frontiers in Pharmacology,  14  (1148410).  [PMID:37288112]
7. Mengyang Wang, Xue Han, Tianxiang Yu, Minxiu Wang, Wu Luo, Chunpeng Zou, Xiuyun Li, Gao Li, Gaojun Wu, Yi Wang, Guang Liang.  (2023)  OTUD1 promotes pathological cardiac remodeling and heart failure by targeting STAT3 in cardiomyocytes.  Theranostics,  13  (7): ( 2263–2280).  [PMID:37153745]
8. Tian-Lun Wen, Jia-Hui Bai, Ming-Mai Bao, Yong Qin, Yue Su, Yin-Long Guo.  (2023)  Ultrasonic sample introduction combined with flame assisted thermal ionization: Pretreatment-free direct mass spectrometry analysis for fraction collecting tubes of preparative liquid chromatography.  TALANTA,  259  (124508).  [PMID:37043878]
9. Weiwei Zhu, Minxiu Wang, Leiming Jin, Bin Yang, Bin Bai, Rumbidzai Natasha Mutsinze, Wei Zuo, Nipon Chattipakorn, Joo Young Huh, Guang Liang, Yi Wang.  (2022)  Licochalcone A protects against LPS-induced inflammation and acute lung injury by directly binding with myeloid differentiation factor 2 (MD2).  BRITISH JOURNAL OF PHARMACOLOGY,  180  (8): (1114-1131).  [PMID:36480410]
10. Siyuan Shen, Gaojun Wu, Wu Luo, Weixin Li, Xiaobo Li, Chengyi Dai, Weijian Huang, Guang Liang.  (2023)  Leonurine attenuates angiotensin II-induced cardiac injury and dysfunction via inhibiting MAPK and NF-κB pathway.  PHYTOMEDICINE,  108  (154519).  [PMID:36332391]
11. Kai-Wen Ren, Xiao-Hong Yu, Yu-Hui Gu, Xin Xie, Yu Wang, Shi-hao Wang, Hui-Hua Li, Hai-Lian Bi.  (2022)  Cardiac-specific knockdown of Bhlhe40 attenuates angiotensin II (Ang II)-Induced atrial fibrillation in mice.  Frontiers in Cardiovascular Medicine,  9  (957903).  [PMID:36304536]
12. Na Yang, Chunpeng Zou, Wu Luo, Diyun Xu, Mengyang Wang, Yi Wang, Gaojun Wu, Peiren Shan, Guang Liang.  (2022)  Sclareol attenuates angiotensin II-induced cardiac remodeling and inflammation via inhibiting MAPK signaling.  PHYTOTHERAPY RESEARCH,  37  (2): (578-591).  [PMID:36178264]
13. Yawen Deng, Zhitong Li, Xiangbo An, Rui Fan, Yao Wang, Jiatian Li, Xiaolei Yang, Jiawei Liao, Yunlong Xia.  (2022)  Hyperhomocysteinemia Promotes Cardiac Hypertrophy in Hypertension.  Oxidative Medicine and Cellular Longevity,  2022  (1486157).  [PMID:36046692]
14. Xin Xie, Ting-ting Shen, Hai-lian Bi, Zhuo-lin Su, Zi-qi Liao, Ying Zhang, Lei Shi, Yun-long Xia.  (2022)  Melatonin inhibits angiotensin II–induced atrial fibrillation through preventing degradation of Ang II Type I Receptor–Associated Protein (ATRAP).  BIOCHEMICAL PHARMACOLOGY,  202  (115146).  [PMID:35710020]
15. Mengyang Wang, Wu Luo, Tianxiang Yu, Shiqi Liang, Jinfeng Sun, Yi Zhang, Xue Han, Xiaohong Long, Guang Liang, Gao Li.  (2022)  Corynoline protects ang II-induced hypertensive heart failure by increasing PPARα and Inhibiting NF-κB pathway.  BIOMEDICINE & PHARMACOTHERAPY,  150  (113075).  [PMID:35658238]
16. Guangquan Hu, Xiaojie Ding, Feng Gao, Jiehua Li.  (2022)  Calcium and integrin binding protein 1 (CIB1) induces myocardial fibrosis in myocardial infarction via regulating the PI3K/Akt pathway.  EXPERIMENTAL ANIMALS,      [PMID:34349085]
17. Jinfu Qian, Wu Luo, Chengyi Dai, Jun Wang, Xinfu Guan, Chunpeng Zou, Nipon Chattipakorn, Gaojun Wu, Weijian Huang, Guang Liang.  (2021)  Myeloid differentiation protein 2 mediates angiotensin II-induced inflammation and mesenchymal transition in vascular endothelium.  BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE,  1867  (166043).  [PMID:33338595]
18. Ke Lin, Wu Luo, Jueqian Yan, Siyuan Shen, Qirui Shen, Jun Wang, Xinfu Guan, Gaojun Wu, Weijian Huang, Guang Liang.  (2021)  TLR2 regulates angiotensin II-induced vascular remodeling and EndMT through NF-κB signaling.  Aging-US,  13  (2): ( 2553–2574).  [PMID:33318302]
19. Zhengyong Wang, Yuqi Cao, Yingjie Lu, Fang Zhang, Yue Su, Yinlong Guo.  (2020)  Ultrasonic extraction and nebulization in real-time coupled with carbon fiber ionization mass spectrometry for rapid screening of the synthetic drugs adulterated into herbal products.  ANALYTICA CHIMICA ACTA,  1136  (62).  [PMID:33081950]
20. Guo Xiao, Zhang Yongtao, Lu Changhong, Qu Fengxia, Jiang Xianyan.  (2020)  Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy.  BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY,  84  (4): (714-724).  [PMID:31797747]
21. Rui Guo, Ningning Liu, Hao Liu, Junhua Zhang, Han Zhang, Yingchao Wang, Mirko Baruscotti, Lu Zhao, Yi Wang.  (2020)  High content screening identifies licoisoflavone A as a bioactive compound of Tongmaiyangxin Pills to restrain cardiomyocyte hypertrophy via activating Sirt3.  PHYTOMEDICINE,  68  (153171).  [PMID:32018211]
22. Jing Yang, Wenpeng Zhang, Hongjun Zhang, Minlin Zhong, Wenbo Cao, Zishuai Li, Xi Huang, Zongxiu Nie, Jiaming Liu, Peng Li, Xiaoxiao Ma, Zheng Ouyang.  (2019)  Polydopamine-Modified Substrates for High-Sensitivity Laser Desorption Ionization Mass Spectrometry Imaging.  ACS Applied Materials & Interfaces,  11  (49): (46140–46148).  [PMID:31729222]
23. Xin Xie, Hai-Lian Bi, Song Lai, Yun-Long Zhang, Nan Li, Hua-Jun Cao, Ling Han, Hong-Xia Wang, Hui-Hua Li.  (2019)  The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation.  Science Advances,  5  (5):   [PMID:31086810]
24. Zheng Xu, Chunpeng Zou, Weihui Yu, Sujing Xu, Lan Huang, Zia Khan, Jingying Wang, Guang Liang, Yi Wang.  (2019)  Inhibition of STAT3 activation mediated by toll-like receptor 4 attenuates angiotensin II-induced renal fibrosis and dysfunction.  BRITISH JOURNAL OF PHARMACOLOGY,  176  (14): (2627-2641).  [PMID:30958891]

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