Hydroxyhomosildenafil - 95%, high purity , CAS No.139755-85-4

Item Number

H276052

Grouped product items
SKU	Size	Availability	Price
H276052-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$30.90
H276052-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$92.90
H276052-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$157.90
H276052-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$315.90
H276052-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$536.90
H276052-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$750.90
H276052-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,314.90

Sildenafil analog. Phosphodiesterase type 5 (PDE5) inhibitor.

View related series

Basic Description

Synonyms	Chronadalate LP \| SCHEMBL18416781 \| 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-; 1-Piperazineethanol, 4-[[3-(4,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyri
Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Sildenafil analog. Phosphodiesterase type 5 (PDE5) inhibitor.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Lodenafil is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)

Associated Targets(Human)

PDE5A Tclin cGMP-specific 3',5'-cyclic phosphodiesterase (2 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDE5A Tclin Phosphodiesterase 5A (5113 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PDE3A Tclin Phosphodiesterase 3 (1749 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	5-[2-ethoxy-5-[4-(2-hydroxyethyl)piperazin-1-yl]sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one
INCHI	InChI=1S/C23H32N6O5S/c1-4-6-18-20-21(27(3)26-18)23(31)25-22(24-20)17-15-16(7-8-19(17)34-5-2)35(32,33)29-11-9-28(10-12-29)13-14-30/h7-8,15,30H,4-6,9-14H2,1-3H3,(H,24,25,31)
InChi Key	NEYKRKVLEWKOBI-UHFFFAOYSA-N
Canonical SMILES	CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CCO)OCC)C
Isomeric SMILES	CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CCO)OCC)C
PubChem CID	135452901
Molecular Weight	504.60

Certificates

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot Number	Certificate Type	Date	Item
C2412257	Certificate of Analysis	Dec 05, 2024	H276052
C2412260	Certificate of Analysis	Dec 05, 2024	H276052
C2412262	Certificate of Analysis	Dec 05, 2024	H276052
C2412270	Certificate of Analysis	Dec 05, 2024	H276052
C2412272	Certificate of Analysis	Dec 05, 2024	H276052
C2412274	Certificate of Analysis	Dec 05, 2024	H276052
C2412276	Certificate of Analysis	Dec 05, 2024	H276052
A2412276	Certificate of Analysis	Jan 25, 2024	H276052
C2412255	Certificate of Analysis	Jan 25, 2024	H276052
C2412258	Certificate of Analysis	Jan 25, 2024	H276052
C2412261	Certificate of Analysis	Jan 25, 2024	H276052
C2412269	Certificate of Analysis	Jan 25, 2024	H276052
C2412271	Certificate of Analysis	Jan 25, 2024	H276052
C2412273	Certificate of Analysis	Jan 25, 2024	H276052
C2412275	Certificate of Analysis	Jan 25, 2024	H276052

Show more⌵

Solution Calculators

Determine the necessary mass, volume, or concentration for preparing a solution.

Determine the dilution needed to prepare a stock solution.