Hymenidin - ≥95%, high purity , CAS No.107019-95-4

  • ≥95%
Item Number
H329523
Grouped product items
SKUSizeAvailabilityPrice Qty
H329523-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$245.90

an antagonist of serotonergic receptors and inhibitor of CDK5/p25 and GSK-3β

Basic Description

SynonymsCS-0065697 | 2-DEBROMOOROIDIN | BDBM50456974 | Q27257846 | N-(3-(2-amino-1H-imidazol-4-yl)allyl)-4-bromo-1H-pyrrole-2-carboxamide | HY-118328 | AKOS040748546 | 1H-PYRROLE-2-CARBOXAMIDE, N-((2E)-3-(2-AMINO-1H-IMIDAZOL-5-YL)-2-PROPEN-1-YL)-4-BROMO- | 1H-Pyr
Specifications & Purity≥95%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Hymenidin is an antagonist of serotonergic receptors and has antiprotozoal activity. Additionally, hymenidin inhibits Cdk5/p35 (IC|50|= 4 μM) and GSK-3β (IC|50|= 12 μM).

Associated Targets(Human)

KCNA6 Tclin Potassium voltage-gated channel subfamily A member 6 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNA3 Tclin Potassium voltage-gated channel subfamily A member 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNA4 Tclin Potassium voltage-gated channel subfamily A member 4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNA5 Tclin Potassium voltage-gated channel subfamily A member 5 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNA5 Tclin Voltage-gated potassium channel subunit Kv1.5 (1353 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNA2 Tclin Voltage-gated potassium channel subunit Kv1.2 (28 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNA3 Tclin Voltage-gated potassium channel subunit Kv1.3 (1067 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNA1 Tclin Voltage-gated potassium channel subunit Kv1.1 (248 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SH-SY5Y (11521 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNA6 Tclin Voltage-gated potassium channel subunit Kv1.6 (20 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNA4 Tclin Voltage-gated potassium channel subunit Kv1.4 (24 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mycobacterium tuberculosis (203094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BV-2 (3710 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Kcna6 Potassium voltage-gated channel subfamily A member 6 (27 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Kcna2 Potassium voltage-gated channel subfamily A member 2 (23 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Kcna5 Potassium voltage-gated channel subfamily A member 5 (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Kcnh1 Potassium voltage-gated channel subfamily H member 1 (18 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name N-[(E)-3-(2-amino-1H-imidazol-5-yl)prop-2-enyl]-4-bromo-1H-pyrrole-2-carboxamide
INCHI InChI=1S/C11H12BrN5O/c12-7-4-9(15-5-7)10(18)14-3-1-2-8-6-16-11(13)17-8/h1-2,4-6,15H,3H2,(H,14,18)(H3,13,16,17)/b2-1+
InChi Key KHJREOQCERRAME-OWOJBTEDSA-N
Canonical SMILES C1=C(NC=C1Br)C(=O)NCC=CC2=CN=C(N2)N
Isomeric SMILES C1=C(NC=C1Br)C(=O)NC/C=C/C2=CN=C(N2)N
PubChem CID 6439099
Molecular Weight 310.15

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in DMSO, and 100% ethanol.
Refractive Indexn20D1.74 (Predicted)
Boil Point(°C)578.30° C (Predicted)
Melt Point(°C)249.17° C (Predicted)

Related Documents

Solution Calculators