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Hyperforin - 98%, high purity , CAS No.11079-53-1, Agonist of Pregnane X receptor;Activator of TRPC6

Moligand™
≥98%

CAS#: 11079-53-1
Formula: C₃₅H₅₂O₄
Molecular Weight: 536.78
PubChem CID: 441298

Item Number

H275963

Grouped product items
SKU	Size	Availability	Price
H275963-1mg	1mg	In stock	$289.90
H275963-500μg	500μg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$188.90
H275963-5mg	5mg	In stock	$1,303.90

'Description': "Key constituent of St. John's wort", 'Alternative names': ' Hyp-DCHA Hyperforin-DCHA

View related series

Pregnane X receptor Agonist TRPC6 Activator

Basic Description

Synonyms	hyperforin\|11079-53-1\|hiperforina\|hyperforine\|CHEBI:5834\|RM741E34FP\|CHEMBL1237210\|(1R,5S,6R,7S)-4-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione\|(+)-Hyperforin\|(1R,5S,6R
Specifications & Purity	98%
Storage Temp	Protected from light,Store at -20°C,Desiccated
Shipped In	Dry ice
Grade	Moligand™
Action Type	ACTIVATOR, AGONIST
Mechanism of action	Agonist of Pregnane X receptor;Activator of TRPC6
Product Description	Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes.

Associated Targets

TRPC6 Tchem Short transient receptor potential channel 6 0 Activities

Discover Target: TRPC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR1I2 Tchem Nuclear receptor subfamily 1 group I member 2 3 Activities

Discover Target: NR1I2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(1R,5R,7S,8R)-4-hydroxy-8-methyl-3,5,7-tris(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-1-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione
INCHI	InChI=1S/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-27,37H,12,16-17,19-21H2,1-11H3/t27-,33+,34+,35-/m0/s1
InChi Key	KGSZHKRKHXOAMG-HQKKAZOISA-N
Canonical SMILES	CC(C)C(=O)C12C(=O)C(=C(C(C1=O)(CC(C2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C
Isomeric SMILES	CC(C)C(=O)[C@]12C(=O)C(=C([C@](C1=O)(C[C@@H]([C@@]2(C)CCC=C(C)C)CC=C(C)C)CC=C(C)C)O)CC=C(C)C
WGK Germany	2
Alternate CAS	238074-03-8
PubChem CID	441298
Molecular Weight	536.78

ChEBI

CAS Registry No.

Wikipedia

PubChem CID

NURSA Ligand

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
F2229365	Certificate of Analysis	Apr 14, 2023	H275963
F2229366	Certificate of Analysis	Apr 14, 2023	H275963
F2229367	Certificate of Analysis	Apr 14, 2023	H275963

Solubility

Soluble in ethanol and in DMSO to 10 mM

Sensitivity

air and light sensitive

Flash Point(°F)

48.2 °F

Flash Point(°C)

9 °C

Safety and Hazards(GHS)

Signal	Danger
Hazard Statements	H225:Highly Flammable liquid and vapor H370:Causes damage to organs
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P403+P235:Store in a well-ventilated place. Keep cool.
WGK Germany	2
RIDADR	UN1230-class3-PG2-Methanol

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