Ibrutinib (PCI-32765) - ≥98%, high purity , Tyrosine-protein kinase BTK inhibitor, CAS No.936563-96-1, Tyrosine-protein kinase BTK inhibitor

Item Number

P127143

• Synonyms: PCI32765 | 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one | 1-{(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1- yl}prop-2-en-1-one | AC-26942 | BI164531 | Ibrutinib-
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: PCI-32765 is a high potent irreversible BTK inhibitor with an IC50 of 0.46 nM for the purified Btk.Highly potent, irreversible Bruton tyrosine kinase (BTK)\xa0inhibitor (IC 50 = 0.5nM). Inhibits autophosphorylation of BTK IC 50 = 11 nM), and phophorylatio
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Tyrosine-protein kinase BTK inhibitor
• Note: Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Ibrutinib is a potent and highly selective Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM, modestly potent to Bmx, CSK, FGR, BRK, HCK, less potent to EGFR, Yes, ErbB2, JAK3, etc.