ID 8 - 98%, high purity , CAS No.147591-46-6

  • ≥98%
Item Number
I287101
Grouped product items
SKUSizeAvailabilityPrice Qty
I287101-5mg
5mg
In stock
$48.90
I287101-10mg
10mg
In stock
$68.90
I287101-25mg
25mg
In stock
$155.90
I287101-50mg
50mg
In stock
$197.90
I287101-100mg
100mg
In stock
$355.90
I287101-250mg
250mg
In stock
$801.90
I287101-1g
1g
In stock
$2,883.90

Sustains self-renewal and pluripotency of ESCs

Basic Description

SynonymsBCP27795 | ID-8 | VVZNWYXIOADGSW-UHFFFAOYSA-N | 1H-Indol-6-ol, 1-(4-methoxyphenyl)-2-methyl-3-nitro- | AKOS000558433 | MLS006011013 | 3-nitro-1-(4-methoxyphenyl)-2-methyl-1H-indol-6-ol | CBDivE_013358 | FT-0729107 | ID-8, >=98% (HPLC) | J-008372 | SW22013
Specifications & Purity≥98%
Biochemical and Physiological MechanismsSustains self-renewal and pluripotency of mouse embryonic stem cells (ESCs)in vitro. Stimulates proliferation at a steady rate (observed in serum-free media supplemented with 10μM over a 30 day period). Also supports human PSC maintenance in combiantions
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CSNK1D Tchem Casein kinase I delta (4546 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CSNK1E Tclin Casein kinase I epsilon (1412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CDK2 Tchem Cyclin-dependent kinase 2 (9050 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK1A Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 1A (6484 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AURKA Tchem Serine/threonine-protein kinase Aurora-A (10240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CLK1 Tchem Dual specificty protein kinase CLK1 (2189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CLK2 Tchem Dual specificity protein kinase CLK2 (3942 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CLK3 Tchem Dual specificity protein kinase CLK3 (2711 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CLK4 Tchem Dual specificity protein kinase CLK4 (4053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U2OS (164939 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK2 Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 2 (2095 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK3 Tchem Dual-specificity tyrosine-phosphorylation regulated kinase 3 (1018 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK1B Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 1B (2654 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DYRK4 Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 4 (692 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BRD4 Tchem Bromodomain-containing protein 4 (13122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CDK5 Tchem Cyclin-dependent kinase 5/CDK5 activator 1 (3697 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TRIM24 Tchem Transcription intermediary factor 1-alpha (2087 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BRPF1 Tchem Peregrin (2217 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK-293T (167025 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fgfr3 Fibroblast growth factor receptor 3 (21 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-22 (3261 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488191483
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488191483
IUPAC Name 1-(4-methoxyphenyl)-2-methyl-3-nitroindol-6-ol
INCHI InChI=1S/C16H14N2O4/c1-10-16(18(20)21)14-8-5-12(19)9-15(14)17(10)11-3-6-13(22-2)7-4-11/h3-9,19H,1-2H3
InChi Key VVZNWYXIOADGSW-UHFFFAOYSA-N
Canonical SMILES CC1=C(C2=C(N1C3=CC=C(C=C3)OC)C=C(C=C2)O)[N+](=O)[O-]
Isomeric SMILES CC1=C(C2=C(N1C3=CC=C(C=C3)OC)C=C(C=C2)O)[N+](=O)[O-]
PubChem CID 791637
Molecular Weight 298.29

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

14 results found

Lot NumberCertificate TypeDateItem
E23061077Certificate of AnalysisMar 30, 2023 I287101
E23061078Certificate of AnalysisMar 30, 2023 I287101
E23061079Certificate of AnalysisMar 30, 2023 I287101
E23061080Certificate of AnalysisMar 30, 2023 I287101
E23061086Certificate of AnalysisMar 30, 2023 I287101
E23061087Certificate of AnalysisMar 30, 2023 I287101
E23061089Certificate of AnalysisMar 30, 2023 I287101
E23061090Certificate of AnalysisMar 30, 2023 I287101
E23061097Certificate of AnalysisMar 30, 2023 I287101
E23061145Certificate of AnalysisMar 30, 2023 I287101
E23061146Certificate of AnalysisMar 30, 2023 I287101
E23061147Certificate of AnalysisMar 30, 2023 I287101
E23061148Certificate of AnalysisMar 30, 2023 I287101
E23061149Certificate of AnalysisMar 30, 2023 I287101

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Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 29.83, Max Conc. mM: 100
SensitivityLight Sensitive,Heat Sensitive
Melt Point(°C)266 °C(dec.)

Safety and Hazards(GHS)

Pictogram(s) GHS09,   GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

H400:Very toxic to aquatic life

Precautionary Statements

P273:Avoid release to the environment.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P391:Collect spillage.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

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Solution Calculators