Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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I129330-250mg | 250mg | In stock | $48.90 | |
I129330-1g | 1g | In stock | $96.90 | |
I129330-5g | 5g | In stock | $164.90 | |
I129330-25g | 25g | In stock | $494.90 | |
I129330-100g | 100g | In stock | $1,479.90 |
Potent antioxidant and neuroprotective agent
Synonyms | BRN 2001459 | IDEBENONE [MART.] | FR114 | Idebenone, >=98% (HPLC) | 2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquinone | 6-(10-Hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinone | HB6PN45W4J | Pharmakon1600-01505755 | SR-01000759378 | Idebenon |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | Idebenone, a neuroprotective agent, has been shown to act as a free radical scavenger and protect mitochondrial membranes against lipid peroxidation. This compound has also been found to prevent platelet aggregation and recover cholinergic and monoaminerg |
Shipped In | Normal |
Mechanism of action | Antioxidant and mitochondrial electron carrier |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant. application: Idebenone has been used:to treat mutant myocilin (mMYOC) cells for drug treatment assay,to validate C2C12 secondary cell screening assay to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs |
ALogP | 4.3 |
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Pubchem Sid | 488179783 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179783 |
IUPAC Name | 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione |
INCHI | InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3 |
InChi Key | JGPMMRGNQUBGND-UHFFFAOYSA-N |
Canonical SMILES | CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO |
Isomeric SMILES | CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO |
RTECS | GU5290000 |
PubChem CID | 3686 |
Molecular Weight | 338.44 |
Reaxy-Rn | 2001459 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
H2414503 | Certificate of Analysis | Aug 02, 2024 | I129330 |
H2414504 | Certificate of Analysis | Aug 02, 2024 | I129330 |
H2414505 | Certificate of Analysis | Aug 02, 2024 | I129330 |
H2414506 | Certificate of Analysis | Aug 02, 2024 | I129330 |
K2129117 | Certificate of Analysis | Sep 21, 2023 | I129330 |
K2129293 | Certificate of Analysis | Sep 21, 2023 | I129330 |
K2130119 | Certificate of Analysis | Sep 21, 2023 | I129330 |
K2316055 | Certificate of Analysis | Sep 21, 2023 | I129330 |
K2118109 | Certificate of Analysis | Sep 14, 2023 | I129330 |
E2128345 | Certificate of Analysis | Mar 10, 2023 | I129330 |
C1525022 | Certificate of Analysis | Oct 14, 2022 | I129330 |
C23211003 | Certificate of Analysis | Oct 30, 2021 | I129330 |
D2303485 | Certificate of Analysis | Oct 30, 2021 | I129330 |
Solubility | Soluble in DMSO (>25 mg/ml), ethanol (>25 mg/ml), methanol, and chloroform. Insoluble in water. |
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Melt Point(°C) | 53℃ |
RTECS | GU5290000 |
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Reaxy-Rn | 2001459 |
Merck Index | 4888 |
Starting at $285.90
Starting at $45.90
Starting at $285.90
1. Zhiwen Li, Zhilin Zhou, Jianghua Wang, Tingxian Tao, Yingqiang Fu. (2023) Aggregation-induced emission enhancement N, S-CQDs for selective detection of CIP in the environment. NANOTECHNOLOGY, 34 (39): (395503). [PMID:37343538] |
1. Zhiwen Li, Zhilin Zhou, Jianghua Wang, Tingxian Tao, Yingqiang Fu. (2023) Aggregation-induced emission enhancement N, S-CQDs for selective detection of CIP in the environment. NANOTECHNOLOGY, 34 (39): (395503). [PMID:37343538] |