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Idebenone - ≥98%, high purity , Antioxidant and mitochondrial electron carrier, CAS No.58186-27-9, Antioxidant and mitochondrial electron carrier

  • ≥98%
Item Number
I129330
Grouped product items
SKUSizeAvailabilityPrice Qty
I129330-250mg
250mg
In stock
$48.90
I129330-1g
1g
In stock
$96.90
I129330-5g
5g
In stock
$164.90
I129330-25g
25g
In stock
$494.90
I129330-100g
100g
In stock
$1,479.90

Potent antioxidant and neuroprotective agent

Basic Description

Synonymsidebenone|58186-27-9|2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione|Idebenona|Idebenonum|Sovrima|hydroxydecyl ubiquinone|CV 2619|CV-2619|Oristar hdu|BRN 2001459|CHEBI:31687|2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-1,4-benzoquino
Specifications & Purity≥98%
Biochemical and Physiological MechanismsIdebenone, a neuroprotective agent, has been shown to act as a free radical scavenger and protect mitochondrial membranes against lipid peroxidation. This compound has also been found to prevent platelet aggregation and recover cholinergic and monoaminerg
Shipped InNormal
Mechanism of actionAntioxidant and mitochondrial electron carrier
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant.
An antioxidant and neuroprotective agent.


application:

Idebenone has been used:to treat mutant myocilin (mMYOC) cells for drug treatment assay,to validate C2C12 secondary cell screening assay

to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs

Product Properties

ALogP4.3

Names and Identifiers

Pubchem Sid488179783
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179783
IUPAC Name 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
INCHI InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
InChi Key JGPMMRGNQUBGND-UHFFFAOYSA-N
Canonical SMILES CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
Isomeric SMILES CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCCO
RTECS GU5290000
PubChem CID 3686
Molecular Weight 338.44
Reaxy-Rn 2001459

Certificates

Certificate of Analysis(COA)

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13 results found

Lot NumberCertificate TypeDateItem
H2414503Certificate of AnalysisAug 02, 2024 I129330
H2414504Certificate of AnalysisAug 02, 2024 I129330
H2414505Certificate of AnalysisAug 02, 2024 I129330
H2414506Certificate of AnalysisAug 02, 2024 I129330
K2129117Certificate of AnalysisSep 21, 2023 I129330
K2129293Certificate of AnalysisSep 21, 2023 I129330
K2130119Certificate of AnalysisSep 21, 2023 I129330
K2316055Certificate of AnalysisSep 21, 2023 I129330
K2118109Certificate of AnalysisSep 14, 2023 I129330
E2128345Certificate of AnalysisMar 10, 2023 I129330
C1525022Certificate of AnalysisOct 14, 2022 I129330
C23211003Certificate of AnalysisOct 30, 2021 I129330
D2303485Certificate of AnalysisOct 30, 2021 I129330

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Chemical and Physical Properties

SolubilitySoluble in DMSO (>25 mg/ml), ethanol (>25 mg/ml), methanol, and chloroform. Insoluble in water.
Melt Point(°C)53℃

Safety and Hazards(GHS)

RTECS GU5290000
Reaxy-Rn 2001459
Merck Index 4888

Related Documents

Solution Calculators