| 1. Boulanger MJ, Chow DC, Brevnova EE, Garcia KC. (2003) Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex.. Science, 300 (5628): (2101-4). [PMID:12829785] |
| 2. Shaw S, Bourne T, Meier C, Carrington B, Gelinas R, Henry A, Popplewell A, Adams R, Baker T, Rapecki S et al.. (2014) Discovery and characterization of olokizumab: a humanized antibody targeting interleukin-6 and neutralizing gp130-signaling.. MAbs, 6 (3): (774-82). [PMID:24670876] |
| 3. Kang S, Tanaka T, Narazaki M, Kishimoto T. (2019) Targeting Interleukin-6 Signaling in Clinic.. Immunity, 50 (4): (1007-1023). [PMID:30995492] |
| 4. Q Y Chen. (1992-09-01) [Stable and efficient expression of human interleukin-6 cDNA in mammalian cells after gene transfer].. Zhonghua zhong liu za zhi [Chinese journal of oncology], 14 ((5)): (340-344). [PMID:1291290] |
| 5. H C van Zaanen,R P Koopmans,L A Aarden,H J Rensink,J M Stouthard,S O Warnaar,H M Lokhorst,M H van Oers. (1996-09-15) Endogenous interleukin 6 production in multiple myeloma patients treated with chimeric monoclonal anti-IL6 antibodies indicates the existence of a positive feed-back loop.. The Journal of clinical investigation, 98 ((6)): (1441-1448). [PMID:8823310] |
| 6. Kim D, Won HY, Hwang ES, Kim YK, Choo HP.. (2017) Synthesis of benzoxazole derivatives as interleukin-6 antagonists.. Bioorg Med Chem, 25 (12): (3127-3134). [PMID:28442260] |
| 7. May, L T LT, Shaw, J E JE, Khanna, A K AK, Zabriskie, J B JB and Sehgal, P B PB.. (1991) Marked cell-type-specific differences in glycosylation of human interleukin-6.. Cytokine, [PMID:1883960] |
| 8. Lütticken, C C, Krüttgen, A A, Möller, C C, Heinrich, P C PC and Rose-John, S S.. (1991) Evidence for the importance of a positive charge and an alpha-helical structure of the C-terminus for biological activity of human IL-6.. FEBS letters, (6): [PMID:2037043] |
| 9. Clogston, C L CL, Boone, T C TC, Crandall, B C BC, Mendiaz, E A EA and Lu, H S HS.. (1989) Disulfide structures of human interleukin-6 are similar to those of human granulocyte colony stimulating factor.. Archives of biochemistry and biophysics, [PMID:2472117] |
| 10. Ming, J E JE, Cernetti, C C, Steinman, R M RM and Granelli-Piperno, A A.. (1989) Interleukin 6 is the principal cytolytic T lymphocyte differentiation factor for thymocytes in human leukocyte conditioned medium.. The Journal of molecular and cellular immunology : JMCI, [PMID:2610854] |
| 11. Tonouchi, N N, Miwa, K K, Karasuyama, H H and Matsui, H H.. (1989) Deletion of 3' untranslated region of human BSF-2 mRNA causes stabilization of the mRNA and high-level expression in mouse NIH3T3 cells.. Biochemical and biophysical research communications, (15): [PMID:2789513] |
| 12. Zilberstein, A A, Ruggieri, R R, Korn, J H JH and Revel, M M.. (1986) Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.. The EMBO journal, [PMID:3023045] |
| 13. Wong, G G GG, Witek-Giannotti, J J, Hewick, R M RM, Clark, S C SC and Ogawa, M M.. (1988) Interleukin 6: identification as a hematopoietic colony-stimulating factor.. Behring Institute Mitteilungen, [PMID:3266463] |
| 14. Van Damme, J J and 5 more authors.. (1988) Separation and comparison of two monokines with lymphocyte-activating factor activity: IL-1 beta and hybridoma growth factor (HGF). Identification of leukocyte-derived HGF as IL-6.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:3279116] |
| 15. Brakenhoff, J P JP, de Groot, E R ER, Evers, R F RF, Pannekoek, H H and Aarden, L A LA.. (1987) Molecular cloning and expression of hybridoma growth factor in Escherichia coli.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:3320204] |
| 16. Hirano, T T and 9 more authors.. (1986) Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin.. Nature, [PMID:3491322] |
| 17. Yasukawa, K K and 6 more authors.. (1987) Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene.. The EMBO journal, [PMID:3500852] |
| 18. May, L T LT, Helfgott, D C DC and Sehgal, P B PB.. (1986) Anti-beta-interferon antibodies inhibit the increased expression of HLA-B7 mRNA in tumor necrosis factor-treated human fibroblasts: structural studies of the beta 2 interferon involved.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3538015] |
| 19. Haegeman, G G and 5 more authors.. (1986) Structural analysis of the sequence coding for an inducible 26-kDa protein in human fibroblasts.. European journal of biochemistry, (15): [PMID:3758081] |
| 20. Breton, J J and 8 more authors.. (1995) Structure, stability and biological properties of a N-terminally truncated form of recombinant human interleukin-6 containing a single disulfide bond.. European journal of biochemistry, (15): [PMID:7851440] |
| 21. Nishimura, C C, Watanabe, A A, Gouda, H H, Shimada, I I and Arata, Y Y.. (1996) Folding topologies of human interleukin-6 and its mutants as studied by NMR spectroscopy.. Biochemistry, (9): [PMID:8555185] |
| 22. Somers, W W, Stahl, M M and Seehra, J S JS.. (1997) 1.9 A crystal structure of interleukin 6: implications for a novel mode of receptor dimerization and signaling.. The EMBO journal, (3): [PMID:9118960] |
| 23. Xu, G Y GY and 6 more authors.. (1997) Solution structure of recombinant human interleukin-6.. Journal of molecular biology, (2): [PMID:9159484] |
| 24. Fishman, D D and 6 more authors.. (1998) The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.. The Journal of clinical investigation, (1): [PMID:9769329] |
| 25. Foster, C B CB and 11 more authors.. (2000) An IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in men infected with human immunodeficiency virus.. Blood, (1): [PMID:11001912] |
| 26. Ota, N N and 8 more authors.. (2001) A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density.. Journal of human genetics, [PMID:11355017] |
| 27. Chung, Hye Won HW and 8 more authors.. (2003) Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women.. Journal of human genetics, [PMID:12768442] |
| 28. Nakahara, Hideko H and 6 more authors.. (2003) Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis.. Arthritis and rheumatism, [PMID:12794819] |
| 29. Nemeth, Elizabeta E and 6 more authors.. (2004) IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin.. The Journal of clinical investigation, [PMID:15124018] |
| 30. Wolsk, Emil E, Mygind, Helene H, Grøndahl, Thomas S TS, Pedersen, Bente K BK and van Hall, Gerrit G.. (2010) IL-6 selectively stimulates fat metabolism in human skeletal muscle.. American journal of physiology. Endocrinology and metabolism, [PMID:20823453] |
| 31. Ellingsgaard, Helga H and 20 more authors.. (2011) Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells.. Nature medicine, (30): [PMID:22037645] |
| 32. Taniguchi, Koji K and 17 more authors.. (2015) A gp130-Src-YAP module links inflammation to epithelial regeneration.. Nature, (5): [PMID:25731159] |
| 33. Tagliabracci, Vincent S VS and 14 more authors.. (2015) A Single Kinase Generates the Majority of the Secreted Phosphoproteome.. Cell, (18): [PMID:26091039] |
| 34. Larsen, Jakob Vejby JV and Petersen, Claus Munck CM.. (2017) SorLA in Interleukin-6 Signaling and Turnover.. Molecular and cellular biology, (1): [PMID:28265003] |
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