illudalic acid , CAS No.I611033, Inhibitor of RTP Type F

Item Number
I611033
Grouped product items
SKUSizeAvailabilityPrice Qty
I611033-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
I611033-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
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RTP Type F Inhibitor

Basic Description

SynonymsUNII-HW3U676A69 | 3,6-dihydroxy-8,8-dimethyl-1-oxo-1,3,4,7,8,9-hexahydro-cyclopenta(h)isochromene-5-carbaldehyde | Illudalic acid | 1,3,4,7,8,9-Hexahydro-3,6-dihydroxy-8,8-dimethyl-1-oxocyclopenta(H)-2-benzopyran-5-carboxaldehyde | illudalate | GTPL8770 |
Specifications & PurityMoligand™
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of RTP Type F

Associated Targets(Human)

PTPRF Tchem Receptor-type tyrosine-protein phosphatase F (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTPN2 Tchem T-cell protein-tyrosine phosphatase (1317 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DUSP3 Tchem Dual specificity protein phosphatase 3 (1161 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPN7 Tchem Protein-tyrosine phosphatase LC-PTP (886 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPN11 Tchem Protein-tyrosine phosphatase 2C (2297 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPRC Tchem Leukocyte common antigen (2317 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPRF Tchem Receptor-type tyrosine-protein phosphatase F (LAR) (718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DUSP22 Tbio Dual specificity phosphatase 22 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPRE Tbio Receptor-type tyrosine-protein phosphatase epsilon (68 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name 3,6-dihydroxy-8,8-dimethyl-1-oxo-3,4,7,9-tetrahydrocyclopenta[h]isochromene-5-carbaldehyde
INCHI InChI=1S/C15H16O5/c1-15(2)4-8-9(5-15)13(18)10(6-16)7-3-11(17)20-14(19)12(7)8/h6,11,17-18H,3-5H2,1-2H3
InChi Key BDEDPKFUFGCVCJ-UHFFFAOYSA-N
Canonical SMILES O=Cc1c(O)c2CC(Cc2c2c1CC(O)OC2=O)(C)C
Isomeric SMILES CC1(CC2=C3C(=C(C(=C2C1)O)C=O)CC(OC3=O)O)C
PubChem CID 3653077

Certificates

Certificate of Analysis(COA)

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Related Documents

References

1. Ling Q, Huang Y, Zhou Y, Cai Z, Xiong B, Zhang Y, Ma L, Wang X, Li X, Li J et al..  (2008)  Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action..  Bioorg Med Chem,  16  (15): (7399-409).  [PMID:18579388] [10.1021/op500134e]
2. Yang X, Li J, Zhou Y, Shen Q, Chen J, Li J.  (2005)  Discovery of novel inhibitor of human leukocyte common antigen-related phosphatase..  Biochim Biophys Acta,  1726  (1): (34-41).  [PMID:16198483] [10.1021/op500134e]

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