illudalic acid , CAS No.I611033, Inhibitor of RTP Type F

Item Number
I611033
Grouped product items
SKUSizeAvailabilityPrice Qty
I611033-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
I611033-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90
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RTP Type F Inhibitor

Basic Description

SynonymsIlludalic acid | HW3U676A69 | 18508-77-5 | UNII-HW3U676A69 | CHEMBL506661 | 3,6-dihydroxy-8,8-dimethyl-1-oxo-3,4,7,9-tetrahydrocyclopenta[h]isochromene-5-carbaldehyde | 1,3,4,7,8,9-Hexahydro-3,6-dihydroxy-8,8-dimethyl-1-oxocyclopenta(H)-2-benzopyran-5-carboxaldehyde |
Specifications & PurityMoligand™
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of RTP Type F

Associated Targets(Human)

PTPRF Tchem Receptor-type tyrosine-protein phosphatase F (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTPN2 Tchem T-cell protein-tyrosine phosphatase (1317 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DUSP3 Tchem Dual specificity protein phosphatase 3 (1161 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPN7 Tchem Protein-tyrosine phosphatase LC-PTP (886 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPN11 Tchem Protein-tyrosine phosphatase 2C (2297 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPRC Tchem Leukocyte common antigen (2317 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPRF Tchem Receptor-type tyrosine-protein phosphatase F (LAR) (718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DUSP22 Tbio Dual specificity phosphatase 22 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPRE Tbio Receptor-type tyrosine-protein phosphatase epsilon (68 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTPRM Tchem Receptor-type tyrosine-protein phosphatase mu (41 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 3,6-dihydroxy-8,8-dimethyl-1-oxo-3,4,7,9-tetrahydrocyclopenta[h]isochromene-5-carbaldehyde
INCHI InChI=1S/C15H16O5/c1-15(2)4-8-9(5-15)13(18)10(6-16)7-3-11(17)20-14(19)12(7)8/h6,11,17-18H,3-5H2,1-2H3
InChi Key BDEDPKFUFGCVCJ-UHFFFAOYSA-N
Canonical SMILES O=Cc1c(O)c2CC(Cc2c2c1CC(O)OC2=O)(C)C
Isomeric SMILES CC1(CC2=C3C(=C(C(=C2C1)O)C=O)CC(OC3=O)O)C
PubChem CID 3653077

Certificates

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Related Documents

References

1. Ling Q, Huang Y, Zhou Y, Cai Z, Xiong B, Zhang Y, Ma L, Wang X, Li X, Li J et al..  (2008)  Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action..  Bioorg Med Chem,  16  (15): (7399-409).  [PMID:18579388]
2. Yang X, Li J, Zhou Y, Shen Q, Chen J, Li J.  (2005)  Discovery of novel inhibitor of human leukocyte common antigen-related phosphatase..  Biochim Biophys Acta,  1726  (1): (34-41).  [PMID:16198483]

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