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Imatinib Mesylate (STI571) - ≥99%, high purity , Stem cell growth factor receptor inhibitor, CAS No.220127-57-1, Stem cell growth factor receptor inhibitor

Specifications & Purity:  ≥99%
Item Number
I129225
Grouped product items
SKUSizeAvailabilityPrice Qty
I129225-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$20.90
I129225-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$42.90
I129225-1g
1g
In stock
$142.90
I129225-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$253.90
I129225-25g
25g
In stock
$1,143.90
I129225-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$4,114.90

Discover Imatinib Mesylate (STI571) by Aladdin Scientific in ≥99% for only $20.90. Available - in Ligands at Aladdin Scientific. Potent, selective tyrosine kinase inhibitor Tags: Piperazines, Six-Membered Heterocyclic Compounds.

Basic Description

SynonymsImatinib mesylate|220127-57-1|Gleevec|Glivec|Imatinib mesilate|imatinib methanesulfonate|sti-571|Imatinib Mesylate (STI571)|Imatinib accord|Imatinib medac|Imatinib (mesylate)|imatinib monomesylate|Shantinib|Imatinib (as mesilate)|NSC-716051|QTI-571|Imatin
Specifications & Purity≥99%
Storage TempStore at 2-8°C
Shipped InWet ice
Action TypeINHIBITOR
Mechanism of actionStem cell growth factor receptor inhibitor

Names and Identifiers

IUPAC Name methanesulfonic acid;4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
INCHI InChI=1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34);1H3,(H,2,3,4)
InChi Key YLMAHDNUQAMNNX-UHFFFAOYSA-N
Canonical SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
Isomeric SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
WGK Germany 3
PubChem CID 123596
Molecular Weight 589.71

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot NumberCertificate TypeDateItem
E2223170Certificate of AnalysisMar 14, 2024 I129225
E2223171Certificate of AnalysisMar 14, 2024 I129225
E2223174Certificate of AnalysisMar 14, 2024 I129225
K1915031Certificate of AnalysisJun 09, 2023 I129225
D2101062Certificate of AnalysisJan 13, 2023 I129225
D2101064Certificate of AnalysisJan 13, 2023 I129225
A1512020Certificate of AnalysisSep 17, 2022 I129225
E2223172Certificate of AnalysisFeb 28, 2022 I129225

Chemical and Physical Properties

SolubilitySoluble in water (200 mg/ml), ethanol (~0.2 mg/ml), DMSO (200 mg/ml), DMF (~10 mg/ml), and methanol (sparingly).

Safety and Hazards(GHS)

Pictogram(s) GHS08,GHS07
Signal Danger
Hazard Statements H351,H302,H360
Precautionary Statements P280,P405,P501,P264,P270,P330,P203,P301+P317,P318
WGK Germany 3

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References

1. Battaglia CR et al..  (2020)  Corticotropin-releasing hormone (CRH) alters mitochondrial morphology and function by activating the NF-kB-DRP1 axis in hippocampal neurons..  Cell Death Dis,  11  (11): (1004).  [PMID:33230105]
2. Higa-Nakamine S et al..  (2020)  Fyn-mediated phosphorylation of Pyk2 promotes its activation and dissociation downstream of gonadotropin-releasing hormone receptor..  FEBS J,  287  (16): (3551-3564).  [PMID:31994829]

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