Grouped product items

SKU

Size

Availability

Price

Qty

R134429-50mg

50mg

In stock

$24.90

R134429-250mg

250mg

In stock

$101.90

Basic Description

Synonyms	(5R,6S)-3-((2-Formimidamidoethyl)thio)-6-((R)-1-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate \| IMIPENEM HYDRATE [JAN] \| IMIPENEM MONOHYDRATE [USP-RS] \| (5R,6S)-6-[(1R)-1-hydroxyethyl]-3-[(2-methanimidamidoethyl)sulfanyl]-7-o
Specifications & Purity	≥95%(HPLC)
Biochemical and Physiological Mechanisms	Imipenem monohydrate is a broad spectrum B-lactam antibiotic. It is a member of the carbapenem class of "magic bullet" antibiotics for severe infections.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets(Human)

DPEP1 Tclin Renal dipeptidase (55 Activities)

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ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)

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ABCB11 Tchem Bile salt export pump (2311 Activities)

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ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 Activities)

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ABCC4 Tchem Multidrug resistance-associated protein 4 (785 Activities)

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Associated Targets(non-human)

Streptococcus pneumoniae (31063 Activities)

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Enterococcus (1748 Activities)

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Pseudomonas (460 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Enterobacter cloacae (7976 Activities)

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Klebsiella (302 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Proteus (150 Activities)

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Proteus vulgaris (5823 Activities)

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Salmonella typhimurium (15756 Activities)

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Bacteroides fragilis (1445 Activities)

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Bacteroides thetaiotaomicron (562 Activities)

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Staphylococcus aureus (210822 Activities)

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Staphylococcus epidermidis (22802 Activities)

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Acinetobacter calcoaceticus (618 Activities)

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Citrobacter freundii (1864 Activities)

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Enterobacter (462 Activities)

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Klebsiella aerogenes (4963 Activities)

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Escherichia coli (133304 Activities)

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Morganella morganii (1291 Activities)

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Proteus mirabilis (3894 Activities)

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Serratia (189 Activities)

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Serratia marcescens (3237 Activities)

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Haemophilus influenzae (8812 Activities)

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Streptococcus pyogenes (16140 Activities)

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Enterococcus faecium (13803 Activities)

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Clostridioides difficile (2968 Activities)

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Hathewaya histolytica (12 Activities)

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Clostridium perfringens (1165 Activities)

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Enterococcus faecalis (29875 Activities)

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Mus musculus (284745 Activities)

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Rattus norvegicus (775804 Activities)

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Stenotrophomonas maltophilia (1743 Activities)

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Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(5R,6S)-3-[2-(aminomethylideneamino)ethylsulfanyl]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;hydrate
INCHI	InChI=1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1
InChi Key	GSOSVVULSKVSLQ-JJVRHELESA-N
Canonical SMILES	CC(C1C2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O.O
Isomeric SMILES	C[C@H]([C@@H]1[C@H]2CC(=C(N2C1=O)C(=O)O)SCCN=CN)O.O
WGK Germany	3
PubChem CID	5282372
Molecular Weight	317.36

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
J2429075	Certificate of Analysis	Nov 02, 2024	R134429
K21171187	Certificate of Analysis	Sep 14, 2023	R134429
C2314530	Certificate of Analysis	Sep 04, 2021	R134429
K21171188	Certificate of Analysis	Sep 04, 2021	R134429

Chemical and Physical Properties

Solubility	Soluble in water at 5mg/ml

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS09
Signal	Danger
Hazard Statements	H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P284:[In case of inadequate ventilation] Wear respiratory protection. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P391:Collect spillage. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.
WGK Germany	3

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Imipenem monohydrate - ≥95% (HPLC), high purity , CAS No.74431-23-5

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Solution Calculators

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