Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
I347553-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $137.90 | |
I347553-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $584.90 |
a strong and highly selective histamine H3 receptor agonist
Synonyms | 4-(1H-imidazol-5-ylmethyl)pyridine | Immethridine | GTPL4024 | Q6004930 | UNII-F8ZT2IBM1X | 4-((1H-Imidazol-5-yl)methyl)pyridine | DTXSID401027207 | Pyridine, 4-(1H-imidazol-5-ylmethyl)- | 4-(1H-imidazol-4-yl-methyl)-pyridine | SB17136 | SCHEMBL845141 | C |
---|---|
Specifications & Purity | Moligand™ |
Storage Temp | Room temperature,Desiccated |
Shipped In | Normal |
Grade | Moligand™ |
Action Type | AGONIST |
Mechanism of action | Agonist of H 3 receptor |
Product Description | Immethridine dihydrobromide is a strong and highly selective histamine H|3|receptor agonist (pEC|50|= 9.74) that displays 300-fold selectivity over the H|4|receptor (pK|i|values are 9.07 and 6.61 respectively). Immethridine dihydrobromide does not bind to H|1|or H|2|receptors at concentrations up to 10 μM. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
---|
IUPAC Name | 4-(1H-imidazol-5-ylmethyl)pyridine |
---|---|
INCHI | InChI=1S/C9H9N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h1-4,6-7H,5H2,(H,11,12) |
InChi Key | DFVSGZHJSIEEQQ-UHFFFAOYSA-N |
Canonical SMILES | C1=CN=CC=C1CC2=CN=CN2 |
Isomeric SMILES | C1=CN=CC=C1CC2=CN=CN2 |
PubChem CID | 9989505 |
Molecular Weight | 159.19 |
Wikipedia | Immethridine |
---|---|
CAS Registry No. | 87976-03-2 |
PubChem CID | 9989505 |
ChEMBL Ligand | CHEMBL82298 |
GPCRdb Ligand | immethridine |
Enter Lot Number to search for COA:
Solubility | Soluble to 100 mM in Water |
---|
Pictogram(s) | GHS07 |
---|---|
Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |