Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | Indole-2-carboxylic acid | 1H-Indole-2-carboxylic acid | 1477-50-5 | 2-Carboxyindole | 2-Indolecarboxylic acid | MFCD00005611 | Indol-2-Carboxylic Acid | 2-INDOLYLFORMIC ACID | 1H-indole-2-carboxylicacid | Indole-2-carboxylicAcid-13C | CHEMBL278390 | 137497-03-1 | N-[4-(2-Pyridi |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Reactant for total synthesis of (±)-dibromophakellin and analogs，Reactant for synthesis of the pyrrolizidine alkaloid (±)-trachelanthamidine，Reactant for stereoselective preparation of renieramycin G analogs, Reactant for preparation of spirooxoindolepyrrolidines via reduction of indole-2-carboxylic acid followed by oxidation, condensation, reduction, amidation and Kharasch radical cyclization,Reactant for Pd-catalyzed cyclization,Reactant for preparation of N,N′-(pentane)diylbis[indolecarboxamide] and N,N′-[phenylenebis(methylene)]bis[indolecarboxamide] derivatives |
Associated Targets(Human)
SRD5A2 Tclin 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (1 Activities)
DAO Tchem D-amino-acid oxidase (1 Activities)
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SRD5A1 Tclin Steroid 5-alpha-reductase 1 (755 Activities)
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SRD5A2 Tclin Steroid 5-alpha-reductase 2 (937 Activities)
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MCL1 Tchem Induced myeloid leukemia cell differentiation protein Mcl-1 (3820 Activities)
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HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)
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DAO Tchem D-amino-acid oxidase (802 Activities)
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DDO Tchem D-aspartate oxidase (120 Activities)
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KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
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GMNN Tbio Geminin (128009 Activities)
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SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
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SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
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USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
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Associated Targets(non-human)
HD1 Histone deacetylase (38 Activities)
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Pseudomonas aeruginosa (123386 Activities)
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Klebsiella pneumoniae (43867 Activities)
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Staphylococcus aureus (210822 Activities)
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Acinetobacter baumannii (41033 Activities)
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Escherichia coli (133304 Activities)
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Cryptococcus neoformans (21258 Activities)
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Candida albicans (78123 Activities)
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rep Replicase polyprotein 1ab (378 Activities)
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Mapt Microtubule-associated protein tau (6 Activities)
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NS3 NS3 (1121 Activities)
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Grin1 Glutamate NMDA receptor (6467 Activities)
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SARS-CoV-2 (38078 Activities)
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Names and Identifiers
| IUPAC Name | 1H-indole-2-carboxylic acid |
|---|---|
| INCHI | InChI=1S/C9H7NO2/c11-9(12)8-5-6-3-1-2-4-7(6)10-8/h1-5,10H,(H,11,12) |
| InChi Key | HCUARRIEZVDMPT-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC=C2C(=C1)C=C(N2)C(=O)O |
| Isomeric SMILES | C1=CC=C2C(=C1)C=C(N2)C(=O)O |
| WGK Germany | 3 |
| PubChem CID | 72899 |
| Molecular Weight | 161.16 |
| Beilstein | 124132 |
| Reaxy-Rn | 124132 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Sensitivity | air sensitive |
|---|---|
| Melt Point(°C) | 202-206°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| Reaxy-Rn | 124132 |