Indolmycin is a naturally occurring antibiotic that acts against|Staphylococci|and|Helicobacter pylori.|The compound is a secondary metabolite of|Streptomyces griseus|with the ability to inhibit bacterial tryptophanyl-tRNA synthetase.
1.Hurdle JG, O'Neill AJ, Chopra I. (2004) Anti-staphylococcal activity of indolmycin, a potential topical agent for control of staphylococcal infections.. J Antimicrob Chemother, 54 (2):(549-52). [PMID:15243028]
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3.Pasaje CF, Cheung V, Kennedy K, Lim EE, Baell JB, Griffin MD, Ralph SA. (2016) Selective inhibition of apicoplast tryptophanyl-tRNA synthetase causes delayed death in Plasmodium falciparum.. Sci Rep, 6 (13):(27531). [PMID:27277538]
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