Indophagolin - 98%, high purity , CAS No.1207660-00-1

Item Number

I413408

Grouped product items
SKU	Size	Availability	Price
I413408-5mg	5mg	In stock	$296.90
I413408-10mg	10mg	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	$474.90
I413408-25mg	25mg	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	$939.90
I413408-50mg	50mg	In stock	$1,434.90
I413408-100mg	100mg	In stock	$2,226.90
I413408-250mg	250mg	In stock	$5,010.90
I413408-1g	1g	In stock	$18,038.90

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4, P2X1 and P2X3 with IC50 of 2.71 μM, 2.40 μM and 3.49 μM, respectively. Indophagolin also antagonizes the Gq-prote
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Information Indophagolin is a potent, indoline-containing autophagy inhibitor with IC50 of 140 nM. Indophagolin antagonizes the purinergic receptor P2X4, P2X1 and P2X3 with IC50 of 2.71 μM, 2.40 μM and 3.49 μM, respectively. Indophagolin also antagonizes the Gq-protein-coupled P2Y4, P2Y6, and P2Y11 receptors with IC50 of 3.4~15.4 μM. Indophagolin has a strong antagonistic effect on serotonin receptor 5-HT6 with IC50 of 1.0 μM.

Names and Identifiers

Pubchem Sid	488201297
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488201297
IUPAC Name	5-bromo-N-[4-chloro-3-(trifluoromethyl)phenyl]-1-(cyclopropanecarbonyl)-2,3-dihydroindole-6-sulfonamide
INCHI	InChI=1S/C19H15BrClF3N2O3S/c20-14-7-11-5-6-26(18(27)10-1-2-10)16(11)9-17(14)30(28,29)25-12-3-4-15(21)13(8-12)19(22,23)24/h3-4,7-10,25H,1-2,5-6H2
InChi Key	OGXJZCDFFBDSJJ-UHFFFAOYSA-N
Canonical SMILES	C1CC1C(=O)N2CCC3=CC(=C(C=C32)S(=O)(=O)NC4=CC(=C(C=C4)Cl)C(F)(F)F)Br
Isomeric SMILES	C1CC1C(=O)N2CCC3=CC(=C(C=C32)S(=O)(=O)NC4=CC(=C(C=C4)Cl)C(F)(F)F)Br
PubChem CID	46504926
Molecular Weight	523.75

Certificates

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14 results found

Lot Number	Certificate Type	Date	Item
C2320979	Certificate of Analysis	Jan 05, 2023	I413408
C2328775	Certificate of Analysis	Jan 05, 2023	I413408
C2328836	Certificate of Analysis	Jan 05, 2023	I413408
C2328837	Certificate of Analysis	Jan 05, 2023	I413408
C2328845	Certificate of Analysis	Jan 05, 2023	I413408
C2328856	Certificate of Analysis	Jan 05, 2023	I413408
C2328859	Certificate of Analysis	Jan 05, 2023	I413408
C2328887	Certificate of Analysis	Jan 05, 2023	I413408
C2328900	Certificate of Analysis	Jan 05, 2023	I413408
C2328913	Certificate of Analysis	Jan 05, 2023	I413408
C2328916	Certificate of Analysis	Jan 05, 2023	I413408
C2328920	Certificate of Analysis	Jan 05, 2023	I413408
C2328928	Certificate of Analysis	Jan 05, 2023	I413408
C2328930	Certificate of Analysis	Jan 05, 2023	I413408

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Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.

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