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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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I412147-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $39.90 | |
I412147-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $121.90 | |
I412147-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $210.90 | |
I412147-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $376.90 | |
I412147-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $627.90 |
Synonyms | CS-0007476 | Indotecan(LMP400) | LMP400 | LMP-400 | LMP400; LMP-400; LMP 400 | HY-18351 | 3-[(Morpholine)-1-propyl]-5,3-dimethoxy-8,9-meth ylenedioxy-5,11-dioxo-11H-indeno[1,2-c]isoquinoline | AKOS040741879 | NSC-724998LMP-400 | UNII-BTA69L5M8D | BTA69L5M |
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Specifications & Purity | ≥98% |
Storage Temp | Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Product Description | Information Indotecan (LMP-400, NSC-724998) is a potent topoisomerase 1(Top1) inhibitor with IC50 of 300 nM, 1200 nM, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 15,16-dimethoxy-20-(3-morpholin-4-ylpropyl)-5,7-dioxa-20-azapentacyclo[10.8.0.02,10.04,8.013,18]icosa-1(12),2,4(8),9,13,15,17-heptaene-11,19-dione |
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INCHI | InChI=1S/C26H26N2O7/c1-31-19-10-15-18(13-20(19)32-2)26(30)28(5-3-4-27-6-8-33-9-7-27)24-16-11-21-22(35-14-34-21)12-17(16)25(29)23(15)24/h10-13H,3-9,14H2,1-2H3 |
InChi Key | FMFIFGLHVOZDEL-UHFFFAOYSA-N |
Canonical SMILES | COC1=C(C=C2C(=C1)C3=C(C4=CC5=C(C=C4C3=O)OCO5)N(C2=O)CCCN6CCOCC6)OC |
Isomeric SMILES | COC1=C(C=C2C(=C1)C3=C(C4=CC5=C(C=C4C3=O)OCO5)N(C2=O)CCCN6CCOCC6)OC |
PubChem CID | 11533060 |
Molecular Weight | 478.49 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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I2404535 | Certificate of Analysis | Jun 04, 2024 | I412147 |
I2404536 | Certificate of Analysis | Jun 04, 2024 | I412147 |
I2404537 | Certificate of Analysis | Jun 04, 2024 | I412147 |
I2404538 | Certificate of Analysis | Jun 04, 2024 | I412147 |
I2404539 | Certificate of Analysis | Jun 04, 2024 | I412147 |
I2404540 | Certificate of Analysis | Jun 04, 2024 | I412147 |
I2404541 | Certificate of Analysis | Jun 04, 2024 | I412147 |
I2404564 | Certificate of Analysis | Jun 04, 2024 | I412147 |
I2404565 | Certificate of Analysis | Jun 04, 2024 | I412147 |
I2404566 | Certificate of Analysis | Jun 04, 2024 | I412147 |