Grouped product items

SKU

Size

Availability

Price

Qty

I424909-1ml

1ml

Available within 4-8 weeks(?)

$45.90

Basic Description

Synonyms	inosine \| 58-63-9 \| Hypoxanthosine \| Ribonosine \| Atorel \| Oxiamin \| Hypoxanthine riboside \| Trophicardyl \| Selfer \| Pantholic-L \| Panholic-L \| beta-Inosine \| Hypoxanthine D-riboside \| (-)-Inosine \| Hypoxanthine ribonucleoside \| 9-beta-D-Ribofuranosylhypoxanthine \| Hypoxanthine nucleosi
Specifications & Purity	Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms	Purine nucleoside and adenosine metabolite. Cell-permeable. Displays neuroprotective and immunomodulatory effects. Potent vasodilator and axon growth stimulator.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™

Associated Targets(Human)

ADA Tclin Adenosine deaminase (129 Activities)

Discover Target: ADA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

DU-145 (51482 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MCF7 (126967 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HaCaT (4069 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC22A1 Tchem Solute carrier family 22 member 1 (646 Activities)

Discover Target: SLC22A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMN1 Tchem Survival motor neuron protein (34246 Activities)

Discover Target: SMN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)

Discover Target: SMAD3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)

Discover Target: MBNL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)

Discover Target: BAZ2B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ATXN2 Tbio Ataxin-2 (54410 Activities)

Discover Target: ATXN2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)

Discover Target: IDH1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Ahcy Adenosylhomocysteinase (45 Activities)

Discover Target: Ahcy

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Pnp Purine nucleoside phosphorylase (4 Activities)

Discover Target: Pnp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Spinacia oleracea (250 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trichomonas vaginalis (2376 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

J774.A1 (2436 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Vero (26788 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

C6 (2371 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

L6 (7924 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Perknaster fuscus (7 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ileum (29 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FTL Ferritin light chain (43324 Activities)

Discover Target: FTL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
INCHI	InChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7-,10-/m1/s1
InChi Key	UGQMRVRMYYASKQ-KQYNXXCUSA-N
Canonical SMILES	OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3C(=O)NC=Nc23
Isomeric SMILES	C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
WGK Germany	2
RTECS	NM7460000
PubChem CID	135398641
Molecular Weight	268.23
Beilstein	624896
Reaxy-Rn	624896

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

Specific Rotation[α]	-52 ° (C=1, H2O)
Melt Point(°C)	218°C

Safety and Hazards(GHS)

WGK Germany	2
RTECS	NM7460000
Reaxy-Rn	624896
Merck Index	4975

Citations of This Product

1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729]
2. Wei Jia, Jiying Zhu. (2023) Molecular Mechanism of ε-Polylysine Treatment of Animal-Derived Foods: Glycine Amidinotransferase Activity Implicates Upregulation of l-Arginine and Creatine. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (41): (15106–15120). [PMID:37793042]
3. Depeng Li, Meihong Zhang, A.La Teng Zhu La, Zhengtian Lyu, Xin Li, Yuqing Feng, Dan Liu, Yuming Guo, Yongfei Hu. (2023) Quercetin-enriched Lactobacillus aviarius alleviates hyperuricemia by hydrolase-mediated degradation of purine nucleosides. PHARMACOLOGICAL RESEARCH, 196 (20): (106928). [PMID:37717681]
4. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang. (2023) A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr.. JOURNAL OF SEPARATION SCIENCE, 46 (21): (2300090). [PMID:37688342]
5. Weiliang Guan, Wenqian Nong, Xiaobo Wei, Renchi Chen, Zhihai Huang, Yuting Ding, Xiaoming Qin, Luyun Cai, Linchun Mao. (2023) Influences of two transport strategies on AMPK mediated metabolism and flesh quality of shrimp (Litopenaeus vannamei). JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, [PMID:37658680]
6. Hongyuan Wu, Zhuolan Xu, Danni Xiong, Xinguang Qin, Gang Liu, Haizhi Zhang. (2023) Two dimensional iron metal-organic framework nanosheet with peroxidase-mimicking activity for colorimetric detection of hypoxanthine related to shrimp freshness. TALANTA, 265 (124833). [PMID:37348352]
7. Meng Chu, Yichao Qin, Xiuying Lin, Li Ma, Dehai Deng, Daizhu Lv, Pengcheng Fu, Huan Lin. (2023) A Preliminary Survey of Transfer RNA Modifications and Modifying Enzymes of the Tropical Plant Cocos nucifera L.. Genes, 14 (6): (1287). [PMID:37372467]
8. Hongyuan Zhao, Xiaoyu Chen, Fanqiang Meng, Libang Zhou, Xinyi Pang, Zhaoxin Lu, Yingjian Lu. (2023) Ameliorative effect of Lacticaseibacillus rhamnosus Fmb14 from Chinese yogurt on hyperuricemia. Food Science and Human Wellness, 12 (1379). [PMID:]
9. Guorong Cheng, Zhiqiang Liu, Zhong Zheng, Fengrui Song, Xiaoyu Zhuang, Shu Liu. (2022) Cell Metabolomics Reveals the Potential Mechanism of Aloe Emodin and Emodin Inhibiting Breast Cancer Metastasis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (22): (13738). [PMID:36430215]
10. Fenghua Chen, Chenmei Yang, Xinyu Cheng, Yingjie Fan, Xinyuan Chen, Shizhao Ren, Rongrong Xue. (2022) Explanation for the selective crystallization from inosine solutions using mid-frequency Raman difference spectra analysis. RSC Advances, 12 (29): (18301-18306). [PMID:35799925]
11. Jia-Xin Lin, Tao Xiong, Zhen Peng, Mingyong Xie, Fei Peng. (2022) Novel lactic acid bacteria with anti-hyperuricemia ability: Screening and in vitro probiotic characteristics. Food Bioscience, 49 (101840). [PMID:]
12. Yan Wu, Kaixing Luo, Yanjuan Liu, Wei Chen, Zhengwu Bai, Sheng Tang. (2022) Innovative preparation of ureido/dodecyl dual-functionalized silica as a versatile mixed-mode stationary phase for high-resolution chromatographic separations. JOURNAL OF CHROMATOGRAPHY A, 1665 (462834). [PMID:35085896]
13. Zehuai Mou, Zhijin Gao, Yaoping Hu. (2022) Orange emissive carbon dots for fluorescent determination of hypoxanthine in fish. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 269 (120734). [PMID:34922290]
14. Chen Guo, Shuhan You, Changmei Li, Tiantian Chen, Xiudan Wang. (2021) One-Step and Colorimetric Detection of Fish Freshness Indicator Hypoxanthine Based on the Peroxidase Activity of Xanthine Oxidase Grade I Ammonium Sulfate Suspension. Frontiers in Microbiology, 12 (791227). [PMID:34925300]
15. Qing Wang,Mao Ye,Li Xu,Zhi-guo Shi. (2015-09-01) A reversed-phase/hydrophilic interaction mixed-mode C18-Diol stationary phase for multiple applications.. Analytica chimica acta, 888 (182-190). [PMID:26320974]
16. Hengye Li,Xuemeng Zhang,Lin Zhang,Hui Cang,Fenying Kong,Dahe Fan,Wei Wang. (2018-04-13) Hyperbranched Polyglycerol Functionalized Silica Stationary Phase for Hydrophilic Interaction Liquid Chromatography.. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 34 ((4)): (433-438). [PMID:29643306]

References

1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729]
2. Wei Jia, Jiying Zhu. (2023) Molecular Mechanism of ε-Polylysine Treatment of Animal-Derived Foods: Glycine Amidinotransferase Activity Implicates Upregulation of l-Arginine and Creatine. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 71 (41): (15106–15120). [PMID:37793042]
3. Depeng Li, Meihong Zhang, A.La Teng Zhu La, Zhengtian Lyu, Xin Li, Yuqing Feng, Dan Liu, Yuming Guo, Yongfei Hu. (2023) Quercetin-enriched Lactobacillus aviarius alleviates hyperuricemia by hydrolase-mediated degradation of purine nucleosides. PHARMACOLOGICAL RESEARCH, 196 (20): (106928). [PMID:37717681]
4. Qiangqiang Jia, Zufan Yang, Qian Wang, Haishan Yang, Xiaofeng Tang, Hongyang Zhang, Lingling Cao, Gong Zhang. (2023) A liquid chromatography-tandem mass spectrometry method for comprehensive determination of metabolites in the purine pathway of rat plasma and its application in anti-gout effects of Lycium ruthenicum Murr.. JOURNAL OF SEPARATION SCIENCE, 46 (21): (2300090). [PMID:37688342]
5. Weiliang Guan, Wenqian Nong, Xiaobo Wei, Renchi Chen, Zhihai Huang, Yuting Ding, Xiaoming Qin, Luyun Cai, Linchun Mao. (2023) Influences of two transport strategies on AMPK mediated metabolism and flesh quality of shrimp (Litopenaeus vannamei). JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, [PMID:37658680]
6. Hongyuan Wu, Zhuolan Xu, Danni Xiong, Xinguang Qin, Gang Liu, Haizhi Zhang. (2023) Two dimensional iron metal-organic framework nanosheet with peroxidase-mimicking activity for colorimetric detection of hypoxanthine related to shrimp freshness. TALANTA, 265 (124833). [PMID:37348352]
7. Meng Chu, Yichao Qin, Xiuying Lin, Li Ma, Dehai Deng, Daizhu Lv, Pengcheng Fu, Huan Lin. (2023) A Preliminary Survey of Transfer RNA Modifications and Modifying Enzymes of the Tropical Plant Cocos nucifera L.. Genes, 14 (6): (1287). [PMID:37372467]
8. Hongyuan Zhao, Xiaoyu Chen, Fanqiang Meng, Libang Zhou, Xinyi Pang, Zhaoxin Lu, Yingjian Lu. (2023) Ameliorative effect of Lacticaseibacillus rhamnosus Fmb14 from Chinese yogurt on hyperuricemia. Food Science and Human Wellness, 12 (1379). [PMID:]
9. Guorong Cheng, Zhiqiang Liu, Zhong Zheng, Fengrui Song, Xiaoyu Zhuang, Shu Liu. (2022) Cell Metabolomics Reveals the Potential Mechanism of Aloe Emodin and Emodin Inhibiting Breast Cancer Metastasis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23 (22): (13738). [PMID:36430215]
10. Fenghua Chen, Chenmei Yang, Xinyu Cheng, Yingjie Fan, Xinyuan Chen, Shizhao Ren, Rongrong Xue. (2022) Explanation for the selective crystallization from inosine solutions using mid-frequency Raman difference spectra analysis. RSC Advances, 12 (29): (18301-18306). [PMID:35799925]
11. Jia-Xin Lin, Tao Xiong, Zhen Peng, Mingyong Xie, Fei Peng. (2022) Novel lactic acid bacteria with anti-hyperuricemia ability: Screening and in vitro probiotic characteristics. Food Bioscience, 49 (101840). [PMID:]
12. Yan Wu, Kaixing Luo, Yanjuan Liu, Wei Chen, Zhengwu Bai, Sheng Tang. (2022) Innovative preparation of ureido/dodecyl dual-functionalized silica as a versatile mixed-mode stationary phase for high-resolution chromatographic separations. JOURNAL OF CHROMATOGRAPHY A, 1665 (462834). [PMID:35085896]
13. Zehuai Mou, Zhijin Gao, Yaoping Hu. (2022) Orange emissive carbon dots for fluorescent determination of hypoxanthine in fish. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 269 (120734). [PMID:34922290]
14. Chen Guo, Shuhan You, Changmei Li, Tiantian Chen, Xiudan Wang. (2021) One-Step and Colorimetric Detection of Fish Freshness Indicator Hypoxanthine Based on the Peroxidase Activity of Xanthine Oxidase Grade I Ammonium Sulfate Suspension. Frontiers in Microbiology, 12 (791227). [PMID:34925300]
15. Qing Wang,Mao Ye,Li Xu,Zhi-guo Shi. (2015-09-01) A reversed-phase/hydrophilic interaction mixed-mode C18-Diol stationary phase for multiple applications.. Analytica chimica acta, 888 (182-190). [PMID:26320974]
16. Hengye Li,Xuemeng Zhang,Lin Zhang,Hui Cang,Fenying Kong,Dahe Fan,Wei Wang. (2018-04-13) Hyperbranched Polyglycerol Functionalized Silica Stationary Phase for Hydrophilic Interaction Liquid Chromatography.. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 34 ((4)): (433-438). [PMID:29643306]

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.

Inosine - 10mM in DMSO, high purity , CAS No.58-63-9