Iromycin A - ≥98%, high purity , CAS No.213137-53-2

  • ≥98%
Item Number
I275438
Grouped product items
SKUSizeAvailabilityPrice Qty
I275438-1mg
1mg
In stock
$361.90

Selective eNOS inhibitor

Basic Description

SynonymsIROMYCIN A | LQZ8C7MJ7D | 213137-53-2 | NK26588 | NK-26588 | 2(1H)-Pyridinone, 6-((2E,5E)-3,7-dimethyl-2,5-octadienyl)-4-hydroxy-3-methyl-5-propyl- | 4-Hydroxy-6-((E,E)-3,7-dimethylocta-2,5-dienyl)-3-methyl-5-propyl-1H-pyridin-2-one | 6-((2E,5E)-3,7-Dimethyl-2,5-octadi
Specifications & Purity≥98%
Biochemical and Physiological MechanismsSelective eNOS inhibitor. Shows selectivity for eNOS over nNOS. Inhibits thaxtomin biosynthesis. Mitochondrial electron transport chain inhibitor. α-pyridone metabolite.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L929 (3802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NDUFV1 Mitochondrial complex I; NADH oxidoreductase (130 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 6-[(2E,5E)-3,7-dimethylocta-2,5-dienyl]-4-hydroxy-3-methyl-5-propyl-1H-pyridin-2-one
INCHI InChI=1S/C19H29NO2/c1-6-8-16-17(20-19(22)15(5)18(16)21)12-11-14(4)10-7-9-13(2)3/h7,9,11,13H,6,8,10,12H2,1-5H3,(H2,20,21,22)/b9-7+,14-11+
InChi Key HVAVEUHAOCVIPN-DTCTWCMCSA-N
Canonical SMILES CCCC1=C(NC(=O)C(=C1O)C)CC=C(C)CC=CC(C)C
Isomeric SMILES CCCC1=C(NC(=O)C(=C1O)C)C/C=C(\C)/C/C=C/C(C)C
PubChem CID 54732501
Molecular Weight 303.44

Certificates

Certificate of Analysis(COA)

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Lot NumberCertificate TypeDateItem
H2223343Certificate of AnalysisJun 06, 2023 I275438

Chemical and Physical Properties

SolubilitySoluble in DMSO

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Solution Calculators