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Home Microbiology Isavuconazole - 10mM in DMSO, high purity , CAS No.241479-67-4
Isavuconazole - 10mM in DMSO, high purity , CAS No.241479-67-4
a broad-spectrum antifungal
Basic Description Synonyms Isavuconazole|241479-67-4|BAL-4815|isavuconazol|BAL 4815|Isavuconazole [INN]|isavuconazolum|1286730-05-9|CHEBI:85979|UNII-60UTO373KE|60UTO373KE|RO 0094815|4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl Specifications & Purity 10mM in DMSO Storage Temp Store at -80°C Shipped In Dry ice Product Description Isavuconazole is an extended-spectrum triazole with activity against a wide variety of fungal pathogens. Isavuconazole has shown activity against the dimorphic true pathogenic fungi, such as|Blastomyces dermatitidis|and|Histoplasma capsulatum|, and is also active against uncommon dematiaceous fungi such as|Exophiala spp.|and|Phialophora spp.|as well as against dermatophytic species. Isavuconazole showed broad spectrum antifungal activity against FLC-resistant strains of|Candida spp.|,|Aspergillus spp.|and uncommon opportunistic fungal species.
Names and Identifiers IUPAC Name 4-[2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile INCHI InChI=1S/C22H17F2N5OS/c1-14(21-28-20(10-31-21)16-4-2-15(9-25)3-5-16)22(30,11-29-13-26-12-27-29)18-8-17(23)6-7-19(18)24/h2-8,10,12-14,30H,11H2,1H3/t14-,22+/m0/s1 InChi Key DDFOUSQFMYRUQK-RCDICMHDSA-N Canonical SMILES CC(C1=NC(=CS1)C2=CC=C(C=C2)C#N)C(CN3C=NC=N3)(C4=C(C=CC(=C4)F)F)O Isomeric SMILES C[C@@H](C1=NC(=CS1)C2=CC=C(C=C2)C#N)[C@](CN3C=NC=N3)(C4=C(C=CC(=C4)F)F)O PubChem CID 6918485 Molecular Weight 437.47
Safety and Hazards(GHS) Pictogram(s) GHS08 Signal Warning Hazard Statements H361fd: Suspected of damaging fertility; Suspected of damaging the unborn child
Precautionary Statements P280: Wear protective gloves/protective clothing/eye protection/face protection.
P405: Store locked up.
P501: Dispose of contents/container to ...
P201: Obtain special instructions before use.
P308+P313: IF exposed or concerned: Get medical advice/attention.
P202: Do not handle until all safety precautions have been read and understood.
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